Myosin III illuminates the mechanism of arrestin translocation

Neuron
Katherine J Strissel, Vadim Y Arshavsky

Abstract

Recent studies have revealed that light adaptation of both vertebrate and invertebrate photoreceptors is accompanied by massive translocations of major signaling proteins in and out of the cellular compartments where visual signal transduction takes place. In this issue of Neuron, Lee and Montell report a breakthrough in understanding the mechanism of arrestin translocation in Drosophila. They show that arrestin is carried into the light-sensitive microvilli by phosphoinositide-enriched vesicles driven by a myosin motor.

References

Dec 16, 1991·FEBS Letters·K PalczewskiK P Hofmann
Sep 15, 2001·Nature·R C Hardie, P Raghu
Oct 3, 2003·Current Biology : CB·Roger C Hardie
Oct 16, 2003·Science's STKE : Signal Transduction Knowledge Environment·Vadim Y Arshavsky

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Citations

Oct 11, 2005·Annual Review of Cell and Developmental Biology·Verena Niggli
Jun 5, 2008·Cell and Tissue Research·Isabella Spiwoks-BeckerRainer Spessert
Oct 11, 2005·Current Biology : CB·Akiko K Satoh, Donald F Ready
Jun 18, 2005·The Journal of Biological Chemistry·Katherine J StrisselVadim Y Arshavsky
Feb 20, 2007·Annual Review of Physiology·Scott M DeWireSudha K Shenoy
Jun 17, 2020·Journal of Lipid Research·Raju V S Rajala
Feb 9, 2021·Journal of Lipid Research·Raju V S Rajala

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