PMID: 9432076Jan 31, 1998Paper

Myringotomy: a prerequisite for the development of myringosclerosis?

The Laryngoscope
C MattssonS Hellström

Abstract

Streptococcus pneumoniae was inoculated into the left middle-ear cavity in two groups of rats, resulting in purulent otitis media. After 3 days, one group of infected animals and a third group of noninfected animals were subjected to left-sided myringotomy. The tympanic membranes were examined both otomicroscopically and histologically 1 and 3 months later. On otomicroscopic examination the noninfected myringotomized animals had developed extensive myringosclerotic lesions, whereas only minimal sclerotic deposits were noted in the myringotomized animals with acute otitis media (AOM). On histologic examination both the noninfected myringotomized animals and the myringotomized animals with AOM were similar in the frequency and extension of sclerotic lesions in the tympanic membrane. The nonmyringotomized rats with AOM were free of sclerotic lesions, except for minor changes found in one animal.

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Citations

Oct 20, 2010·The Journal of Laryngology and Otology·H AslanS Oztürkcan
Feb 26, 2011·The Journal of Laryngology and Otology·V KahyaO Gedikli
Aug 13, 2002·The Laryngoscope·Jorge SpratleyManuel Pais-Clemente
Mar 16, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Selcuk Cem ErdurakDeniz Kaya
May 6, 2014·International Journal of Pediatric Otorhinolaryngology·Rıza DündarHüseyin Katılmış
Apr 28, 2006·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·K Cagdas KazikdasKazim Onal
Mar 6, 2007·The Laryngoscope·Patricia A HebdaJoseph E Dohar
Dec 22, 2005·International Journal of Pediatric Otorhinolaryngology·Cüneyd UneriMine Yazici
Sep 15, 2005·International Journal of Pediatric Otorhinolaryngology·Giedre RaustyteJens Thomsen
Feb 1, 2002·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Cengiz OzcanIsmail Cinel
Jan 15, 2015·International Journal of Pediatric Otorhinolaryngology·Evin Das SahinAbdulvahap Akyigit
Jul 26, 2016·International Journal of Otolaryngology·Masayuki FurukawaKatsuhisa Ikeda
Aug 16, 2017·The Journal of Laryngology and Otology·Y ZhangA Liu
Sep 11, 2002·Acta Oto-laryngologica·Jorge SpratleyManuel Pais-Clemente
Apr 24, 2002·The Annals of Otology, Rhinology & Laryngology. Supplement·Cuneyt M AlperTomonori Takasaka

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