Myristylation and palmitylation of Src family members: the fats of the matter

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Myristylation and palmitylation of Src family members: the fats of the matter

Abstract

References

Lysine residues form an integral component of a novel NH2-terminal membrane targeting motif for myristylated pp60v-src

Binding of peptides with basic residues to membranes containing acidic phospholipids

Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

Interaction of tyrosine kinase oncoproteins with cellular membranes

Binding of acylated peptides and fatty acids to phospholipid vesicles: pertinence to myristoylated proteins

Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lck and p59fyn mediates interaction with glycosyl-phosphatidylinositol-anchored proteins.

Lipid modifications of G proteins: alpha subunits are palmitoylated

A novel N-terminal motif for palmitoylation of G-protein alpha subunits

Citations

In vivo calcineurin crystals formed using the baculovirus expression system

Mechanism of glucose transport across the human and rat placental barrier: a review

Connexins and E-cadherin are differentially expressed during trophoblast invasion and placenta differentiation in the rat

Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily

Induction in human osteoblastic cells (SaOS2) of the early response genes fos, jun, and myc by the amino terminal fragment (ATF) of urokinase

Human genome project: Italian contribution. Future directions

A shift in protein S-palmitoylation, with persistence of growth-associated substrates, marks a critical period for synaptic plasticity in developing brain

Structure-function relationships in Src family and related protein tyrosine kinases

Prediction of protein cellular attributes using pseudo-amino acid composition

ZmHox: a novel class of maize homeobox genes

Effect of micellar charge on the conformation and dynamics of melittin

Fcepsilon- and Fcgamma-receptor signaling in diseases

Src, Fyn and Yes play differential roles in VEGF-mediated endothelial cell events

Dynamics of lipid raft components during lymphocyte apoptosis: the paradigmatic role of GD3

Optimized bacterial expression and purification of the c-Src catalytic domain for solution NMR studies.

Fatty acyl chain-dependent but charge-independent association of the SH4 domain of Lck with lipid membranes

Ubiquitin is attached to membranes of baculovirus particles by a novel type of phospholipid anchor

Protein tyrosine phosphorylation as a mechanism of signalling in mast cells and basophils

InsP3-dependent Ca2+ oscillations linked to activation of voltage-dependent H+ conductance in Rana esculenta oocytes

Role of Bruton's tyrosine kinase in immunodeficiency

Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis

Identification of GIYWHHY as a novel peptide substrate for human p60c-src protein tyrosine kinase

Fluvastatin inhibits raft dependent Fcgamma receptor signalling in human monocytes

Similar diffusibility of membrane proteins across the axon-soma and dendrite-soma boundaries revealed by a novel FRAP technique

Application of SVM to predict membrane protein types

Myristoylation of viral and bacterial proteins

Electrostatic binding of proteins to membranes. Theoretical predictions and experimental results with charybdotoxin and phospholipid vesicles

Entamoeba histolytica: a beta 1 integrin-like fibronectin receptor assembles a signaling complex similar to those of mammalian cells

Assembly of the CD8alpha/p56(lck) protein complex in stably expressing rat epithelial cells

Use of intracellular pH and annexin-V flow cytometric assays to monitor apoptosis and its suppression by bcl-2 over-expression in hybridoma cell culture

Expression of enzymes of covalent protein modification during regulated and dysregulated proliferation of mammary epithelial cells: PKA, PKC and NMT

Heterogeneous N-terminal acylation of retinal proteins

A versatile microporation technique for the transfection of cultured CNS neurons

A pivotal role of cysteine 3 of Lck tyrosine kinase for localization to glycolipid-enriched microdomains and T cell activation

Phosphorylation and activation of cGMP-dependent protein kinase by Src

Non-receptor protein tyrosine kinases as immune targets of viruses

Highly immunogenic and fully synthetic peptide-carrier constructs targetting GnRH

Degradation of cellular and viral Fos proteins

Protein myristoylation in protein-lipid and protein-protein interactions

Globotriaosyl ceramide (CD77/Gb3) in the glycolipid-enriched membrane domain participates in B-cell receptor-mediated apoptosis by regulating lyn kinase activity in human B cells

Protein kinase C: a paradigm for regulation of protein function by two membrane-targeting modules

MARCKS, membranes, and calmodulin: kinetics of their interaction

Single chain antibodies specific for fatty acids derived from a semi-synthetic phage display library

Structure, alternative splicing, and expression of the human RGS9 gene

Primary structure and function of an A kinase anchoring protein associated with calcium channels

Chimeric constructs containing the SH4/Unique domains of cYes can restrict the ability of Src(527F) to upregulate heme oxygenase-1 expression efficiently

Regulation of cellular signalling by fatty acid acylation and prenylation of signal transduction proteins

Myristoylation

Analysis of the interactions between Nef and cellular proteins

Portrait of a myristoyl switch protein

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