PMID: 9552418Jan 1, 1997Paper
Myt1: a Wee1-type kinase that phosphorylates Cdc2 on residue Thr14
Progress in Cell Cycle Research
A Fattaey, R N Booher
Abstract
Most somatic cell division cycles contain a gap period (G2 phase) between the completion of DNA synthesis and the initiation of mitosis. This delay of mitotic entry is controlled, at least in part, by the repression of Cdc2 kinase activity by the phosphorylation of two conserved residues (Thr14 and Tyr15) within the ATP-binding pocket of the Cdc2 catalytic subunit. The kinases responsible for these two phosphorylation events include the Myt1 and Wee1 kinases, which phosphorylate Cdc2 on Thr14 and Tyr15, respectively. In this discussion, we summarise our current knowledge of the Myt1 kinase and its regulation of Cdc2 kinase activity during the G2-to -M phase transition.
Citations
Sep 6, 2000·Molecular Microbiology·C A Elwell, L A Dreyfus
Nov 6, 2002·Genome Génome / Conseil National De Recherches Canada·Colleen M RadcliffeShelagh D Campbell
Oct 24, 2017·International Journal of Molecular Sciences·Robert CornelisonCharles N Landen
Aug 25, 2018·Proteome Science·Raghuveera Kumar GoelKiven Erique Lukong
Dec 26, 2001·Oncogene·K KoniarasM J O'Connell
Sep 16, 2004·Journal of Cellular Biochemistry·Aruna S Jaiswal, Satya Narayan
Nov 4, 2010·Journal of Neurochemistry·Shin-ichi Hisanaga, Ryo Endo
Aug 23, 2012·PloS One·Michal JesetaJean-François Bodart
Feb 11, 2009·Molecular and Cellular Biology·Hong Seok ChoiZigang Dong
Nov 28, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Yang ZhangBing-Zhi Yu
Jul 14, 2011·Proteomics·Naveid A Ali, Mark P Molloy
Mar 24, 2016·Oncology Reports·Jiming LiuJianwei Jiang
Apr 30, 2015·Journal of Cellular Biochemistry·Armance GelaudeJean-François Bodart
Sep 8, 2016·PloS One·Hung-Chuan ChiuHung-Jen Liu
May 16, 2020·Frontiers in Genetics·Huan-Ping LongGuang Li
Jan 20, 2010·The Journal of Cell Biology·Jeong Su OhMarco Conti
Jan 26, 2013·Development, Growth & Differentiation·Jun IwashitaJun Murata
Feb 23, 2010·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Natalia V KirienkoDavid S Fay
May 20, 2003·The Journal of Biological Chemistry·Tadahiro GodaHideki Kobayashi
Jan 11, 2001·Developmental Biology·T KondoM Yamashita
Jun 8, 2001·Molecular Cell·P T Stukenberg, M W Kirschner
Mar 8, 2002·Cellular Signalling·William D CornwellJeffrey R Jackson
Sep 23, 2003·Cellular Signalling·Shirelyn R BeaumanJohn R Dedman
Mar 10, 2015·Eukaryotic Cell·S D WillgerD A Hogan
Jun 4, 2004·The Journal of Investigative Dermatology·Xiuju DaiKoji Hashimoto
Aug 10, 2005·Developmental Biology·Franck ChesnelJacek Z Kubiak
Sep 20, 2005·Current Biology : CB·Seung Jin HanMarco Conti
Mar 27, 2007·Cell·Sun Young Kim, James E Ferrell
Feb 5, 2011·Molecular Cell·Nicole B TrunnellJames E Ferrell
❮ Previous
Next ❯
Related Concepts
Related Feeds
Related Papers
The Journal of Biological Chemistry
R N BooherA Fattaey
The EMBO Journal
C NorburyP Nurse
Journal of Cell Science
N J WellsT Hunter