n-3 Polyunsaturated fatty acids and mast cell activation

Journal of Leukocyte Biology
Xiaofeng Wang, Marianna Kulka

Abstract

Mast cells are known to play a vital role in the development of inflammation in allergic responses. Recent studies have indicated that mast cell activation could be modulated by n-3 PUFAs, which have a wide range of well-documented health benefits. In our review, we summarize the recent findings and potential mechanisms of the effect of n-3 PUFAs on mast cell activation. This knowledge could provide new strategies for the development of therapeutic interventions for diseases mediated by mast cells.

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Citations

Jul 15, 2015·European Journal of Pharmacology·Andrea DichlbergerWolfgang J Schneider
Jun 14, 2019·Frontiers in Immunology·Philipp M HagemannZane Orinska
Jan 30, 2021·Frontiers in Molecular Biosciences·Shaobing XieWeihong Jiang

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