n-Ethyl Pentylone-Related Deaths in Alabama

Journal of Forensic Sciences
Daniel AthertonRachel Beck

Abstract

n-Ethyl pentylone (NEP) is a chemical substance derived from cathinone. Synthetic cathinones are an evolving group of drugs with stimulating, mind-altering effects sometimes referred to as novel or new psychoactive substances (NPS). There is scarce information in the medical literature regarding forensic cases in which NEP is detected in toxicological testing. We present four fatalities involving NEP from Alabama in 2017. Deaths were attributed to NEP toxicity in two cases (peripheral blood concentrations of 0.121 and 0.953 mg/L) and injuries caused by gunshot wounds in two cases (peripheral blood concentrations of 0.045 and 0.031 mg/L). One case involving NEP described an individual who exhibited classic CNS-stimulant induced erratic behavior before being found dead. These cases enhance the forensic literature regarding specific NPS like NEP and provide contextual reference for professionals considering the significance of NEP in toxicological interpretation.

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Citations

May 17, 2019·Journal of Analytical Toxicology·Anais SerreHélène Peyrière
Jun 28, 2020·Journal of Analytical Toxicology·Timothy LauGail Cooper
Aug 23, 2020·Forensic Science, Medicine, and Pathology·Ellen M F StrömmerMichael D Freeman
Dec 3, 2020·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Piotr Adamowicz
Sep 4, 2020·Therapeutic Drug Monitoring·Nunzia La MaidaMarilyn A Huestis
Dec 17, 2020·Journal of Analytical Toxicology·Alex J KrotulskiBarry K Logan
Apr 16, 2021·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Georgina BlancoSimon H L Thomas
Jun 9, 2021·Archives of Toxicology·Jorge SoaresJoão Paulo Capela

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