N-heterocyclic carbene-catalyzed internal redox reaction of alkynals: an efficient synthesis of allenoates

Organic Letters
Yu-Ming ZhaoJianwei Sun

Abstract

An efficient N-heterocyclic carbene (NHC)-catalyzed internal redox reaction of alkynals that bear a γ leaving group has been developed. This process provides a new access to a range of allenoates in good yields. Preliminary results demonstrate that the enantioselective variant can also be achieved.

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Citations

May 26, 2017·Organic & Biomolecular Chemistry·Qiao RenJian Wang
Jun 12, 2013·Chemistry : a European Journal·Morgan HansLionel Delaude
Jul 23, 2013·Journal of the American Chemical Society·Yuli WangShengming Ma
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May 21, 2015·Chemical Reviews·Darrin M FlaniganTomislav Rovis

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