N-Iodosuccinimide-Promoted Hofmann-Löffler Reactions of Sulfonimides under Visible Light

Organic Letters
Calvin Q O'BroinKilian Muñiz

Abstract

Conditions for an attractive and productive protocol for the position-selective intramolecular C-H amination of aliphatic groups (Hofmann-Löffler reaction) are reported employing sulfonimides as nitrogen sources. N-Iodosuccinimide is the only required promoter for this transformation, which is conveniently initiated by visible light. The overall transformation provides pyrrolidines under mild and selective conditions as demonstrated for 17 different substrates.

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Citations

Apr 6, 2018·Chemical Society Reviews·Yating Zhao, Wujiong Xia
Apr 28, 2016·Chemical Society Reviews·Tao Xiong, Qian Zhang
Apr 10, 2018·Chemical Science·Shyam SathyamoorthiRichard N Zare
Aug 8, 2018·Angewandte Chemie·Christina G Na, Erik J Alexanian
Sep 7, 2018·Chemistry : a European Journal·Estefanía Del CastilloKilian Muñiz
Jul 18, 2019·Angewandte Chemie·Ming-Ming Wang, Jérôme Waser
Sep 14, 2019·Chemical Communications : Chem Comm·Kensuke KiyokawaSatoshi Minakata

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