N-terminal B-type natriuretic peptide levels in pediatric patients with congestive heart failure undergoing cardiac surgery

The Journal of Thoracic and Cardiovascular Surgery
Rowan WalshKaie Ojamaa

Abstract

The objectives of this study were to measure circulating N-terminal B-type natriuretic peptide levels in pediatric patients undergoing surgical repair of congenital heart lesions with left ventricular volume overload and to determine whether presurgical and immediate postoperative N-terminal B-type natriuretic peptide levels could predict patient outcomes after surgical intervention. Thirty-eight children aged 1 to 36 months undergoing surgical repair of cardiac lesions with left ventricular volume overload were studied. Plasma N-terminal B-type natriuretic peptide levels were measured preoperatively and at 2, 12, 24, 48, and 72 hours after surgical intervention and were assessed for their predictive value of postoperative outcomes. Plasma N-terminal B-type natriuretic peptide levels were also measured in 34 similarly aged healthy children. Patient preoperative N-terminal B-type natriuretic peptide levels were significantly higher than those of healthy control subjects (3085 +/- 4046 vs 105 +/- 78 pg/mL). Preoperative N-terminal B-type natriuretic peptide levels correlated with the complexity of surgical repair, as measured by cardiopulmonary bypass time (r = 0.529, P < .001), and with postoperative measures, including fraction...Continue Reading

References

Jan 31, 1989·Biochemical and Biophysical Research Communications·Y SaitoN Minamino
Sep 1, 1996·The Journal of Thoracic and Cardiovascular Surgery·S WanJ L LeClerc
Jul 31, 1998·The New England Journal of Medicine·E R LevinW K Samson
Jul 2, 1999·Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum·J MairB Puschendorf
Jul 19, 2002·The New England Journal of Medicine·Alan S MaiselUNKNOWN Breathing Not Properly Multinational Study Investigators
Sep 12, 2002·Seminars in Nephrology·Hemant DhingraNeil A Kurtzman
Apr 10, 2003·Mayo Clinic Proceedings·Brian P ShapiroMargaret M Redfield
Jun 28, 2003·Pediatrics International : Official Journal of the Japan Pediatric Society·Kenji SudaMasahiko Matsumoto
Feb 13, 2004·The New England Journal of Medicine·Thomas J WangRamachandran S Vasan
Jul 11, 2006·Pediatric Cardiology·Ashish B MadhokD Chowdhury

❮ Previous
Next ❯

Citations

Jan 4, 2012·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Michelle Domico, Paul A Checchia
May 1, 2013·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Massimiliano CantinottiAldo Clerico
Jul 23, 2013·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Michele Domico
Feb 4, 2011·Clinical Chemistry and Laboratory Medicine : CCLM·Massimiliano CantinottiAldo Clerico
Jul 3, 2013·Annals of Cardiac Anaesthesia·Yann Olivier BoegliPhilippe Pouard
Apr 15, 2014·The Annals of Thoracic Surgery·Christoph P HornikUNKNOWN TRIBE-AKI Consortium
Jan 21, 2015·Cardiology in the Young·Massimiliano CantinottiAldo Clerico
Mar 12, 2017·The Journal of Thoracic and Cardiovascular Surgery·Jiangbo QuYanqin Cui
Aug 5, 2016·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Michele Domico, Meredith Allen
Apr 23, 2015·Clinical Chemistry and Laboratory Medicine : CCLM·Massimiliano CantinottiAldo Clerico

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Related Papers

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Elena CarestaCorrado Moretti
Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Massimiliano CantinottiAldo Clerico
Archives of Disease in Childhood. Fetal and Neonatal Edition
Savina MannarinoM Stronah
© 2021 Meta ULC. All rights reserved