PMID: 9697417Aug 11, 1998Paper

N-terminal processing: the methionine aminopeptidase and N alpha-acetyl transferase families

Trends in Biochemical Sciences
R A BradshawK W Walker

Abstract

Removal of the initiator methionine and/or acetylation of the alpha-amino group are among the earliest possible chemical modifications that occur during protein synthesis in eukaryotes. These events are catalyzed by methionine aminopeptidase and N alpha-acetyltransferase, respectively. Recent advances in the isolation and characterization of these enzymes indicate that they exist as isoforms that vary in cellular location, function, and evolutionary origins.

References

Jan 29, 1991·Biochemistry·R Yamada, R A Bradshaw
Sep 1, 1990·Molecular & General Genetics : MGG·N R MovvaC G Miller
Apr 1, 1989·Computer Applications in the Biosciences : CABIOS·D G Higgins, P M Sharp
Jul 1, 1985·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·F ShermanS Tsunasawa
Oct 18, 1988·Biochemistry·S M Arfin, R A Bradshaw
May 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·C G MillerN R Movva
Dec 22, 1970·Biochimica Et Biophysica Acta·J L Brown
Jul 28, 1995·Science·R D FleischmannJ M Merrick
Aug 15, 1995·Proceedings of the National Academy of Sciences of the United States of America·S M ArfinR A Bradshaw
Apr 1, 1994·Trends in Biochemical Sciences·A P Geballe, D R Morris
Mar 29, 1994·Proceedings of the National Academy of Sciences of the United States of America·J F BazanB W Matthews
Dec 19, 1995·Proceedings of the National Academy of Sciences of the United States of America·X Li, Y H Chang
Oct 29, 1996·Proceedings of the National Academy of Sciences of the United States of America·A Varshavsky
Jun 10, 1997·Proceedings of the National Academy of Sciences of the United States of America·N SinC M Crews
Apr 30, 2008·Chemistry : a European Journal·Ross A Widenhoefer

❮ Previous
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Citations

Dec 29, 1998·Protein Science : a Publication of the Protein Society·K W Walker, R A Bradshaw
Mar 31, 2012·Analytical and Bioanalytical Chemistry·Hidetsugu FujigakiKuniaki Saito
Apr 7, 2007·The Journal of Membrane Biology·Shunsuke NoguchiMasaru Kawamura
Feb 10, 2009·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Sanghamitra MitraRichard C Holz
Nov 2, 2004·Angiogenesis·Thomas GarrabrantDana L Johnson
Dec 4, 2003·Biochimie·El Houssine Boufous, Christian Vadeboncoeur
Nov 8, 2003·Bioorganic & Medicinal Chemistry·Maria FardisBrian Hicke
Jun 2, 2005·Cancer Letters·Suzanne Shusterman, John M Maris
Jun 5, 2003·Archives of Biochemistry and Biophysics·Robert L Houtz, Archie R Portis
Jul 20, 2002·Biochemical and Biophysical Research Communications·Yikun LiWeimin Gong
Feb 13, 2001·Molecular and Biochemical Parasitology·A K IngramD Horn
May 3, 2013·Journal of Medicinal Chemistry·Feiran ZhangJun O Liu
Feb 4, 2011·Dalton Transactions : an International Journal of Inorganic Chemistry·Matthieu Rouffet, Seth M Cohen
Jul 19, 2011·Chemical Communications : Chem Comm·Takayuki KatohHiroaki Suga
Apr 2, 1999·European Journal of Biochemistry·M Kobayashi, S Shimizu
Feb 7, 2008·Proceedings of the National Academy of Sciences of the United States of America·Jieyi WangRandy L Bell
May 20, 2009·Proceedings of the National Academy of Sciences of the United States of America·Giselle Román-HernándezTania A Baker
Mar 13, 2013·Proceedings of the National Academy of Sciences of the United States of America·John T NgoDavid A Tirrell
Dec 2, 2009·The Journal of Biological Chemistry·Marcin DragGuy S Salvesen
Aug 2, 2008·The Journal of Biological Chemistry·Sergio C ChaiQi-Zhuang Ye
Sep 25, 2012·Molecular & Cellular Proteomics : MCP·Stefano BonissonePavel A Pevzner
Jan 12, 2010·Molecular & Cellular Proteomics : MCP·Andreas O HelbigAlbert J R Heck
Dec 25, 2012·Molecular & Cellular Proteomics : MCP·Emily D CrawfordJames A Wells
Oct 19, 2011·The Journal of General Physiology·Taekyung KwonThaddeus A Bargiello
Nov 12, 2002·The EMBO Journal·Jun ShengAlexander Varshavsky
Dec 31, 2002·The EMBO Journal·Carmela GiglioneThierry Meinnel
Nov 20, 2010·Journal of the National Cancer Institute·Joong Sup ShimJun O Liu
Aug 22, 2003·Nucleic Acids Research·Yoshihito NiimuraKin-ichiro Miura
Jun 30, 2009·Anti-cancer Drugs·Kazuko TakuboGoshi Shiota
Aug 4, 2004·Genes & Development·Mei-Ling KuoCharles J Sherr
Jul 28, 2006·Cold Spring Harbor Symposia on Quantitative Biology·C J SherrM F Roussel

❮ Previous
Next ❯

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