N2-glucuronidation and N4-acetylation of sulphaphenazole by the turtle Pseudemys scripta elegans

The Veterinary Quarterly
T B VreeM Shimoda

Abstract

After an oral dose of 100 mg of sulphaphenazole, the turtle Pseudemys scripta elegans excretes 27% of the compound unchanged and 3.8% as N4-acetylsulphaphenazole. The expected glucuronide conjugate, sulphaphenazole-N2-glucuronide, is not formed and excreted.

References

Apr 27, 1990·Pharmaceutisch Weekblad. Scientific Edition·T B VreeM Shimoda
Mar 1, 1987·Zentralblatt für Veterinärmedizin. Reihe A·T B VreeJ F Nouws
Sep 1, 1986·Journal of Veterinary Pharmacology and Therapeutics·T B VreeJ F Nouws
Jan 1, 1986·European Journal of Clinical Pharmacology·E G LentjesC A van Ginneken
Oct 1, 1968·The Biochemical Journal·J W BridgesR T Williams
Jun 1, 1970·The Biochemical Journal·R H AdamsonR T Williams
Oct 1, 1971·Chemical & Pharmaceutical Bulletin·M UedaT Koizumi
Feb 1, 1968·Chemical & Pharmaceutical Bulletin·M UedaY Nakagawa
Dec 1, 1964·Nihon juigaku zasshi. The Japanese journal of veterinary science·S Oishi, T Nakajima
Apr 27, 1984·Pharmaceutisch Weekblad. Scientific Edition·T B VreeY A Hekster

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