N4-hydroxycytidine: a mutagen specific for AT to GC transitions.

Mutation Research
C Janion, B W Glickman

Abstract

N4-Hydroxycytidine is a mutagen of the base-analog type and one of the products formed by treatment of cytidine with hydroxylamine. In this communication evidence is presented showing that, in contrast with other known base analogs, N4-hydroxycytidine results mainly, if not exclusively, in AT leads to GC transitional alterations in Escherichia coli K12.

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Citations

Jan 11, 2014·Journal of Colloid and Interface Science·Darius ArndtMarcus Bäumer
Jan 1, 1982·Molecular & General Genetics : MGG·E Sledziewska-Gójska, C Janion
Feb 20, 1989·Journal of Molecular Biology·T BesshoK Negishi
Dec 1, 1994·Mutation Research·K NegishiH Hayatsu
Aug 7, 2013·Journal of Medicinal Chemistry·Laurent F BonnacSteven E Patterson
Dec 25, 2002·Antimicrobial Agents and Chemotherapy·Lieven J StuyverRaymond F Schinazi
May 15, 2021·The Journal of Biological Chemistry·Calvin J GordonMatthias Götte

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