Nabilone for the treatment of paraneoplastic night sweats: a report of four cases

Journal of Palliative Medicine
Vincent Maida

Abstract

ABSTRACT Night sweats are one of many symptoms experienced by patients with advanced cancer. The prevalence of night sweats ranges from 10%-48% in cancer patients. Persistent night sweats tend to decrease quality of life through interference with sleep. A recent study has demonstrated that night sweats occur as part of a symptom pattern, and are associated with the anorexia-cachexia symptom cluster. In addition, night sweats represent one of the symptoms that displays a tendency not to improve as patients with advanced cancer approach end of life. This paper serves to report on the successful management of four patients suffering from persistent paraneoplastic night sweats using the synthetic orally administered cannabinoid nabilone. The four patients had been referred to a regional consultative palliative medicine program and identified night sweats as one of their most significant symptomatic concerns reported on their Edmonton Symptom Assessment System (ESAS) questionnaires.

References

Aug 1, 1981·Journal of Clinical Pharmacology·L H EinhornS D Williams
May 17, 2000·Cancer·V T ChangM Feuerman
Sep 21, 2000·Proceedings of the Society for Experimental Biology and Medicine·T W KleinH Friedman
Apr 16, 2005·The Journal of Pharmacology and Experimental Therapeutics·S A VarvelA H Lichtman
Sep 8, 2005·Urologic Oncology·Davide MauriNicholas Pavlidis
Feb 17, 2006·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Declan Walsh, Lisa Rybicki
Aug 25, 2006·European Journal of Pharmacology·Olov NilssonStig O P Jacobsson
Sep 28, 2006·Annals of Family Medicine·James W MoldZsolt Nagykaldi
Oct 25, 2006·Palliative Medicine·Jaw-Shiun TsaiChing-Yu Chen
Dec 2, 2006·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Mellar DavisJoseph Pergolizzi

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Citations

May 8, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Danielle BrownJanet Schloss
Feb 14, 2019·Journal of Palliative Medicine·Connie CarrSandy Trieu
Mar 17, 2021·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Kaoru NishijimaMasanori Mori

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