Jul 19, 2017

NAD+ : A key metabolic regulator with great therapeutic potential

Journal of Neuroendocrinology
G SultaniN Turner


Nicotinamide adenine dinucleotide (NAD+ ) is a ubiquitous metabolite that serves an essential role in the catabolism of nutrients. Recently, there has been a surge of interest in NAD+ biology, with the recognition that NAD+ influences many biological processes beyond metabolism, including transcription, signalling and cell survival. There are a multitude of pathways involved in the synthesis and breakdown of NAD+ , and alterations in NAD+ homeostasis have emerged as a common feature of a range of disease states. Here, we provide an overview of NAD+ metabolism and summarise progress on the development of NAD+ -related therapeutics.

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Metabolic Process, Cellular
Biochemical Pathway
Transcription, Genetic
Neutrophil Actin Dysfunction
Degenerative Diseases, Spinal Cord
Catabolic Process
Metabolic Pathway

Related Feeds

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.

Related Papers

Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica
T Deguchi
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
Feng Wang, Wei-ping Zhang
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme
T Deguchi
© 2020 Meta ULC. All rights reserved