Naloxone Use Among Emergency Department Patients with Opioid Overdose

The Journal of Emergency Medicine
Catherine A MarcoMichael Ballester

Abstract

Emergency department (ED) visits for unintentional opioid overdoses have increased dramatically. Naloxone hydrochloride (Narcan®) is an opioid antagonist commonly used to treat these overdoses. This study was undertaken to identify experiences regarding naloxone use among ED patients with opioid overdose. This prospective survey study was conducted at an urban level I trauma center. A survey was administered to eligible ED patients after unintentional opioid overdose. This study identified current and previous use of naloxone among ED patients with opioid overdose. Eight-nine ED patients with accidental overdose of opioids participated (90% participation rate). Most participants reported a history of opioid overdose (n = 62 [70%]). A significant minority stated they have had access to a naloxone kit (n = 28 [31%]). Most participants with a naloxone kit stated that their frequency and dosage of opiate use did not change after access to naloxone (n = 17 [63%]), and a few used opiates more often (n = 1 [4%]) or less often (n = 9 [33%]). There was a significant negative correlation between total dose and age (Spearman ρ -0.27; p = 0.01). There was no association between dose and sex. Many patients presenting with opioid overdose ha...Continue Reading

Citations

Apr 8, 2020·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Jeffrey T LaiPeter R Chai
Feb 20, 2019·Substance Abuse Treatment, Prevention, and Policy·Ronald B Moss, Dennis J Carlo
Jun 24, 2020·Peptides·Richard J Bodnar
Mar 21, 2020·The American Journal of Emergency Medicine·Ellen KettlerChristopher J Coyne
Apr 29, 2021·Current Addiction Reports·Ralph FogliaNina A Cooperman
Jun 4, 2021·The International Journal on Drug Policy·Gillian BurtonTessa Parkes

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