Name relearning in elderly patients with schizophrenia: episodic and temporary, not semantic and permanent

Cognitive Neuropsychiatry
T K KondelKeith R Laws

Abstract

Recent reports of lexical-semantic deficits in patients with schizophrenia (Laws, Al-Uzri, & Mortimer, 2000; Laws, McKenna, & Kondel, 1998) suggest that younger patients have problems accessing intact memories and older patients show apparent "loss" of the lexical-semantic memory representations themselves. Picture naming for everyday items was examined in a unique series of elderly patients with schizophrenia (n = 10) with a mean illness duration of 45.5 years; and compared with that in patients with probable Alzheimer's disease (n = 18) and elderly healthy controls (n = 27). Naming consistency across time was used as an indicator of whether the schizophrenic patients had difficulty accessing representations or a loss of the representations themselves. Finally, we examined the ability of the schizophrenic patients to relearn the names of unnamed items across four weekly retraining sessions and to retain them at a one month follow-up. The elderly schizophrenic patients were as anomic as patients with probable Alzheimer's disease. Consistency analysis revealed that the patients had storage deficits. Analysis of patient error types was consistent with a semantic deficit. Finally, the schizophrenic patients showed significant impr...Continue Reading

References

Sep 1, 1993·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·P Faglioni, C Botti
Sep 9, 2000·Schizophrenia Research·K R LawsA M Mortimer
May 7, 2002·Neuropsychologia·Julie S Snowden, David Neary
Jul 16, 2005·Journal of Clinical and Experimental Neuropsychology·Verity C LeesonKeith R Laws
Mar 31, 2006·Cognitive Neuropsychiatry·Mohammed M Al-UzriAnn M Mortimer
Dec 1, 1994·Psychonomic Bulletin & Review·G R Loftus, M E Masson

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Citations

Mar 5, 2009·Journal of Psycholinguistic Research·Adam P VogelDavid A Copland
Dec 8, 2011·Journal of Psychiatry & Neuroscience : JPN·Petra SuchankovaAgneta Ekman
Aug 26, 2006·Schizophrenia Research·Verity C LeesonPeter J McKenna

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