Nano-Enabled Approaches to Chemical Imaging in Biosystems

Annual Review of Analytical Chemistry
Scott T RettererMitchel J Doktycz

Abstract

Understanding and predicting how biosystems function require knowledge about the dynamic physicochemical environments with which they interact and alter by their presence. Yet, identifying specific components, tracking the dynamics of the system, and monitoring local environmental conditions without disrupting biosystem function present significant challenges for analytical measurements. Nanomaterials, by their very size and nature, can act as probes and interfaces to biosystems and offer solutions to some of these challenges. At the nanoscale, material properties emerge that can be exploited for localizing biomolecules and making chemical measurements at cellular and subcellular scales. Here, we review advances in chemical imaging enabled by nanoscale structures, in the use of nanoparticles as chemical and environmental probes, and in the development of micro- and nanoscale fluidic devices to define and manipulate local environments and facilitate chemical measurements of complex biosystems. Integration of these nano-enabled methods will lead to an unprecedented understanding of biosystem function.

References

Feb 1, 1997·Journal of Biomedical Materials Research·S N BhatiaM Toner
May 30, 1997·Science·C S ChenD E Ingber
Jan 14, 2000·Electrophoresis·J C McDonaldG M Whitesides
Oct 21, 2000·Physical Review Letters·J B Pendry
Jun 29, 2001·Nature·S TakayamaG M Whitesides
Mar 29, 2002·Biotechnology and Bioengineering·Mark J PowersLinda G Griffith
Sep 18, 2002·Proceedings of the National Academy of Sciences of the United States of America·Maria E AkermanErkki Ruoslahti
Sep 28, 2002·Science·Todd ThorsenStephen R Quake
Dec 3, 2002·Science·Benoit DubertretAlbert Libchaber
Dec 3, 2002·Nature Biotechnology·Jyoti K JaiswalSanford M Simon
Mar 6, 2003·Chemistry & Biology·Shuichi TakayamaGeorge M Whitesides
Apr 22, 2003·Proceedings of the National Academy of Sciences of the United States of America·Hanbin MaoMichael D Manson
Nov 5, 2003·Nature Biotechnology·Aaron LewisErich Ammann
Dec 12, 2003·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·David Richards
Sep 15, 2004·Analytical Chemistry·Hang LuKlavs F Jensen
Sep 29, 2004·Current Opinion in Chemical Biology·Josefa R Baena, Bernhard Lendl
Nov 24, 2004·Journal of Biomedical Materials Research. Part a·Wei Tan, Tejal A Desai
Dec 8, 2004·Biotechnology and Bioengineering·Paul J HungLuke P Lee
Dec 24, 2004·Lab on a Chip·Anna TourovskaiaAlbert Folch
May 5, 2005·Applied and Environmental Microbiology·J A KloepferJ L Nadeau
Feb 21, 2006·Physical Review Letters·Atsushi OnoSatoshi Kawata
Jun 15, 2006·Journal of the American Chemical Society·Ya-Ping SunSu-Yuan Xie
Nov 9, 2006·Proceedings of the National Academy of Sciences of the United States of America·Juan E KeymerRobert H Austin
Mar 24, 2007·Science·Igor I SmolyaninovChristopher C Davis
Mar 14, 2008·Proceedings of the National Academy of Sciences of the United States of America·Roman StockerMartin F Polz
Aug 12, 2008·Nature·Jason ValentineXiang Zhang
Oct 18, 2008·Science·Vladimir M Shalaev
Nov 1, 2008·Proceedings of the National Academy of Sciences of the United States of America·Delai ChenRustem F Ismagilov
Dec 17, 2008·Proceedings of the National Academy of Sciences of the United States of America·Juan E KeymerRobert H Austin
May 7, 2009·Biotechnology and Bioengineering·Gretchen J MahlerMichael L Shuler
Sep 3, 2009·Journal of the American Chemical Society·Sheng-Tao YangYa-Ping Sun
Dec 1, 2009·Journal of Computational and Theoretical Nanoscience·Alexander HeifetzVadim Backman
Mar 20, 2010·Nature·Jian Feng LiZhong Qun Tian

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
imaging techniques
imaging technologies
optical microscopy
super-resolution microscopies
imaging technique
fluorescence microscopy
scanning
confocal microscopy
surface-enhanced Raman spectroscopy
fluorescence resonance

Software Mentioned

SNOM

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annual Review of Analytical Chemistry
Hatice Ceylan Koydemir, Aydogan Ozcan
Annual Review of Analytical Chemistry
Anisha N Patel, Christine Kranz
Annual Review of Chemical and Biomolecular Engineering
L Robert Middleton, Karen I Winey
Annual Review of Analytical Chemistry
Hunter J Sismaet, Edgar D Goluch
© 2022 Meta ULC. All rights reserved