PMID: 25751006Mar 10, 2015Paper

Nano Traditional Chinese Medicine: Current Progresses and Future Challenges

Current Drug Targets
Yi HuangSongqing Liu

Abstract

Nano traditional Chinese medicine (nano TCM) refers to bioactive ingredients, bioactive parts, medicinal materials or complex prescription, being approximately 100 nm in size, which are processed by nanotechnology. Nano TCM is a product of the TCM modernization, and is an application of nanotechnology in the field of TCM. This article reviews literatures on researches of nano TCM, which were published in the past 15 years. Different nanotechnologies have been used in preparation of Nano TCM in view of the varying aims of the study. The mechanical crushing technology is the main approach for nanolization of TCM material and complex prescription, and nanoparticulate drug delivery systems is the main approach for nanolization of bioactive ingredients or bioactive parts in TCM. Nano TCM has a number of advantages, for example, enhancing the bioavailability of TCM, reducing the adverse effects of TCM, achieving sustained release, attaining targeted delivery, enhancing pharmacological effects and improving the administration route of TCM. However, there are still many problems that must be resolved in nano TCM research. The main challenges to nano TCM include the theory system of TCM modernization, preparation technology, safety and ...Continue Reading

Citations

Jun 8, 2017·Journal of Applied Toxicology : JAT·Hong SuMin Ding
Sep 17, 2019·Dose-response : a Publication of International Hormesis Society·Guojun YanTulin Lu
Aug 6, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·He ZhangGerhard Litscher
Jan 12, 2021·Frontiers in Bioengineering and Biotechnology·Qian SunJing Ma
Apr 23, 2021·Advanced Drug Delivery Reviews·Juan GuanChangyou Zhan

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