Nanofiber membrane of graphene oxide/polyacrylonitrile with highly efficient antibacterial activity

Journal of Biomaterials Science. Polymer Edition
Jia Hui LiWenlong Liu

Abstract

Infection from bacterial resistance to antibiotics has given rise to a grave threat to human health in the world. It is vital to developing highly efficient antibacterial materials that are safe and biocompatible with humans and without bacterial resistance. In this study, nanofiber membranes of graphene oxide/polyacrylonitrile (GO/PAN) with highly efficient antibacterial activity were fabricated via electrospinning technique. As the spindle-knot structure of membranes formed by the addition of GO sheets increased, the hydrophilicity and surface roughness increased. The antibacterial test indicated that antibacterial ratios of 3GO/PAN membranes against Escherichia coli and Staphylococcus aureus were 98.5% and 99.6%, respectively after contracting 24 h, with highly efficient antibacterial activity. Furthermore, the E. coli cell structures of adhered to the GO/PAN nanofiber surface changed significantly shrunk and deformed, and the number of S. aureus cell were obviously less contrast than the pure PAN. The main antibacterial mechanism was GO of spindle-knot in nanofiber membranes produced ROS destroyed the physiological activities of the bacteria lead to death. The fabricated GO/PAN nanofiber membrane of this study is promising ...Continue Reading

References

Apr 8, 2009·Nature Nanotechnology·Sungjin Park, Rodney S Ruoff
Jul 3, 2010·ACS Nano·Wenbing HuChunhai Fan
Sep 2, 2010·Microbiology and Molecular Biology Reviews : MMBR·Julian Davies, Dorothy Davies
Oct 12, 2010·ACS Nano·Omid Akhavan, Elham Ghaderi
Jul 26, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Shaobin LiuYuan Chen
Mar 14, 2013·Advanced Healthcare Materials·Jinming ZhaoChunhai Fan
Apr 29, 2015·Journal of Colloid and Interface Science·Shanshan GuoKoon Gee Neoh
Jan 30, 2016·Journal of the American Chemical Society·Xuefeng ZouYang Luo
Feb 26, 2016·ACS Nano·Kashif RasoolKhaled A Mahmoud
Aug 15, 2017·Journal of Colloid and Interface Science·Zhijun YangYuan Chen
Nov 7, 2017·Environment International·Min QiaoYong-Guan Zhu
Apr 15, 2019·Carbohydrate Polymers·Wenbo CaoZhouping Wang

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