Nanofibril scaffold assisted MEMS artificial hydrogel neuromasts for enhanced sensitivity flow sensing

Scientific Reports
Ajay Giri Prakash KottapalliMichael Triantafyllou

Abstract

We present the development and testing of superficial neuromast-inspired flow sensors that also attain high sensitivity and resolution through a biomimetic hyaulronic acid-based hydrogel cupula dressing. The inspiration comes from the spatially distributed neuromasts of the blind cavefish that live in completely dark undersea caves; the sensors enable the fish to form three-dimensional flow and object maps, enabling them to maneuver efficiently in cluttered environments. A canopy shaped electrospun nanofibril scaffold, inspired by the cupular fibrils, assists the drop-casting process allowing the formation of a prolate spheroid-shaped artificial cupula. Rheological and nanoindentation characterizations showed that the Young's modulus of the artificial cupula closely matches the biological cupula (10-100 Pa). A comparative experimental study conducted to evaluate the sensitivities of the naked hair cell sensor and the cupula-dressed sensor in sensing steady-state flows demonstrated a sensitivity enhancement by 3.5-5 times due to the presence of hydrogel cupula. The novel strategies of sensor development presented in this report are applicable to the design and fabrication of other biomimetic sensors as well. The developed sensor...Continue Reading

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Citations

Dec 15, 2017·Bioinspiration & Biomimetics·Meghali BoraMichael S Triantafyllou
Oct 23, 2018·Advanced Materials·Yei Hwan JungTae-Il Kim
May 21, 2019·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Reza HagihghiMohsen Asadnia
Apr 18, 2019·Bioinspiration & Biomimetics·Yonggang JiangDeyuan Zhang
Apr 23, 2020·Soft Robotics·Johan SundinMarcus Hultmark
May 3, 2018·The Review of Scientific Instruments·B YangD Hu
Jan 16, 2020·Micromachines·Madeshwaran Selvaraj, Kenichi Takahata
Aug 10, 2017·Sensors·Ajay Giri Prakash KottapalliMichael S Triantafyllou
May 21, 2019·Biomimetics·Afroditi Astreinidi BlandinLucia Beccai
Mar 19, 2020·Bioinspiration & Biomimetics·Junzheng ZhengGuangming Xie
Dec 22, 2020·Advanced Materials·Mahdi IlamiHamid Marvi
Mar 15, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Laure FillaudVincent Noel

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