Nanofibrous materials for wound care

Cutaneous and Ocular Toxicology
Wen ZhongHoward I Maibach


Nanofibrous membranes are highly soft materials with high surface-to-volume ratios, and therefore can serve as excellent carriers for therapeutic agents that are antibacterial or accelerate wound healing. This article overviews research and development of nanofibrous dressing materials for wound care, in addition to a discussion of natural and synthetic polymers used in fabricating nanofibrous dressing materials, and a description of in vitro and in vivo evaluation methods for the performance and cytotoxicity of these materials. Natural polymers are usually believed to be less cytotoxic than synthetic polymer in wound care. However, most natural polymers exhibit relatively low mechanical strength than synthetic polymers. As a result, they are usually crosslinked or blended with synthetic polymers so as to somewhat affect their biocompatibility.


Dec 1, 1989·Journal of the American Academy of Dermatology·G CharriereD J Hartmann
Jan 1, 1989·Journal of Biomedical Materials Research·T MiyamotoY Noishiki
Feb 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·I V YannasG F Murphy
Sep 1, 1988·Annals of Surgery·D HeimbachG Warden
Oct 1, 1985·The Journal of Allergy and Clinical Immunology·M DewairK Ziegler
Apr 1, 1984·Journal of the American Academy of Dermatology·L Cooperman, D Michaeli
Apr 1, 1984·Journal of the American Academy of Dermatology·L Cooperman, D Michaeli
Mar 1, 1994·Journal of Biomedical Materials Research·P B van WachemP Nieuwenhuis
Jan 1, 1994·American Journal of Surgery·J C Lawrence
Feb 10, 1998·Journal of Wound Care·L Foster, P Moore
Apr 8, 1999·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·W H EaglsteinM L Sabolinski
Nov 9, 2002·Biomaterials·Gregory H AltmanD L Kaplan
Dec 31, 2002·Biomaterials·El Refaie KenawyGary E Wnek
Oct 22, 2003·Journal of Controlled Release : Official Journal of the Controlled Release Society·Geert VerreckMarcus E Brewster
Nov 5, 2003·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Myung-Seob KhilNarayan Bhattarai
Jul 21, 2004·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Dhirendra S KattiC T Laurencin
Sep 24, 2004·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·A K LynnW Bonfield
Jun 15, 2006·Tissue Engineering·Quynh P PhamAntonios G Mikos
Aug 10, 2007·Journal of Biomedical Materials Research. Part a·Heather M Powell, Steven T Boyce
Aug 19, 2007·Biomacromolecules·Jessica D Schiffman, Caroline L Schauer
Oct 13, 2007·Journal of Biomaterials Science. Polymer Edition·Yuanyuan DuanJun Jia
Dec 7, 2007·Biomaterials·Heather M PowellSteven T Boyce
Apr 24, 2008·Journal of Biomedical Materials Research. Part a·N ShanmugasundaramMary Babu
Apr 24, 2008·Journal of Biomedical Materials Research. Part a·Youliang HongXiabin Jing
Aug 9, 2008·Journal of Controlled Release : Official Journal of the Controlled Release Society·Meital Zilberman, Jonathan J Elsner
Oct 16, 2008·Macromolecular Bioscience·Milena IgnatovaIliya Rashkov
Oct 28, 2008·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·N AdhirajanMary Babu
May 21, 2009·Journal of Biomaterials Science. Polymer Edition·Yasuhiro MatsumotoYoshimitsu Kuroyanagi
May 22, 2009·Biomacromolecules·Kristin SissonJohn F Rabolt
May 29, 2009·Clinical and Experimental Pharmacology & Physiology·Jonathan G MerrellLakshmi S Nair
Jul 28, 2006·Nanotechnology·W E Teo, S Ramakrishna
Aug 13, 2009·Biomedical Materials·Sung Eun KimIl Keun Kwon
Jan 30, 2010·Skin Pharmacology and Physiology·C WiegandU-C Hipler
Jan 28, 2009·ACS Applied Materials & Interfaces·Sergio Torres-GinerJose M Lagaron


Nov 19, 2013·International Journal of Biological Macromolecules·Hyo Won KwakKi Hoon Lee
Oct 19, 2011·Future Medicinal Chemistry·Osama BshenaBert Klumperman
May 31, 2014·International Journal of Nanomedicine·Liangpeng GeMalcolm M Q Xing
Dec 26, 2013·International Journal of Pharmaceutics·George Dan Mogoşanu, Alexandru Mihai Grumezescu
Dec 15, 2010·Cutaneous and Ocular Toxicology·Ferdi Öztürk, Aylin Türel Ermertcan
Apr 1, 2014·Cutaneous and Ocular Toxicology·Wen Zhong
Mar 15, 2011·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Somiraa S SaidLabiba K El-Khordagui
Feb 28, 2015·Advanced Healthcare Materials·Mohammad NorouziMasoud Soleimani
Nov 6, 2015·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Wing P ChanMeng-Yi Bai
Nov 30, 2016·International Journal of Molecular Sciences·Atul A ChaudhariShreekumar R Pillai
Oct 24, 2017·Immunological Investigations·Rakesh Kumar SharmaStanley A Schwartz
Jan 22, 2021·International Journal of Biological Macromolecules·Karine Cappuccio CastroLucia Helena Innocentini Mei
Sep 7, 2018·Life Sciences·Hemen Moradi-SardarehMaliheh Paknejad

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

KIF1A Associated Neurological Disorder

KIF1A associated neurological disorder (KAND) is a rare neurodegenerative condition caused by mutations in the KIF1A gene. KAND may present with a wide range and severity of symptoms including stiff or weak leg muscles, low muscle tone, a lack of muscle coordination and balance, and intellectual disability. Find the latest research on KAND here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.