Nanomaterial-based biosensors using dual transducing elements for solution phase detection

The Analyst
Ning LiYi Lu

Abstract

Biosensors incorporating nanomaterials have demonstrated superior performance compared to their conventional counterparts. Most reported sensors use nanomaterials as a single transducer of signals, while biosensor designs using dual transducing elements have emerged as new approaches to further improve overall sensing performance. This review focuses on recent developments in nanomaterial-based biosensors using dual transducing elements for solution phase detection. The review begins with a brief introduction of the commonly used nanomaterial transducers suitable for designing dual element sensors, including quantum dots, metal nanoparticles, upconversion nanoparticles, graphene, graphene oxide, carbon nanotubes, and carbon nanodots. This is followed by the presentation of the four basic design principles, namely Förster Resonance Energy Transfer (FRET), Amplified Fluorescence Polarization (AFP), Bio-barcode Assay (BCA) and Chemiluminescence (CL), involving either two kinds of nanomaterials, or one nanomaterial and an organic luminescent agent (e.g. organic dyes, luminescent polymers) as dual transducers. Biomolecular and chemical analytes or biological interactions are detected by their control of the assembly and disassembly ...Continue Reading

References

Feb 3, 1998·Nature Biotechnology·S TyagiF R Kramer
Sep 25, 1998·Science·M BruchezA P Alivisatos
Sep 8, 2000·Science·T A TatonR L Letsinger
Apr 3, 2001·Nature Biotechnology·B DubertretA J Libchaber
May 15, 2002·Trends in Biotechnology·Natalia E Broude
Aug 9, 2002·Journal of the American Chemical Society·Dustin J MaxwellShuming Nie
May 29, 2003·Journal of the American Chemical Society·Juewen Liu, Yi Lu
Jan 6, 2004·Nature Biotechnology·Paul Alivisatos
May 13, 2004·Journal of the American Chemical Society·Jwa-Min NamChad A Mirkin
Aug 12, 2004·Journal of the American Chemical Society·Raphaël LévyDavid G Fernig
Oct 8, 2004·Journal of the American Chemical Society·Xiaoyou XuWalter A Scrivens
Oct 23, 2004·Science·K S NovoselovA A Firsov
Nov 13, 2004·Angewandte Chemie·Eugenii Katz, Itamar Willner
Feb 8, 2005·Proceedings of the National Academy of Sciences of the United States of America·Dimitra G GeorganopoulouChad A Mirkin
Mar 3, 2005·Journal of the American Chemical Society·C S YunG F Strouse
Mar 30, 2005·Nano Letters·Christian KirchnerWolfgang J Parak
Apr 2, 2005·Analytical Chemistry·Giridharan GokulranganGeorge S Wilson
Apr 26, 2005·The Analyst·Joseph Wang
Sep 8, 2005·Journal of the American Chemical Society·Juewen Liu, Yi Lu
Oct 11, 2005·Clinica Chimica Acta; International Journal of Clinical Chemistry·C Shad ThaxtonChad A Mirkin
Nov 1, 2005·Analytical Chemistry·Jwa-Min NamJay T Groves
Dec 15, 2005·Analytical Chemistry·C Shad ThaxtonChad A Mirkin
Dec 28, 2005·Nature Materials·Chun-Yang ZhangTza-Huei Wang
Feb 24, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·C LuccardiniM Dahan
Mar 9, 2006·Chemical Reviews·Dimitrios TasisMaurizio Prato
Mar 16, 2006·Analytical Chemistry·Y Paul BaoUwe R Müller
Apr 20, 2006·Journal of the American Chemical Society·T L JenningsG F Strouse
May 11, 2006·Journal of the American Chemical Society·Hao-Xin MaiChun-Hua Yan
Jun 15, 2006·Journal of the American Chemical Society·Ya-Ping SunSu-Yuan Xie
Jun 29, 2006·Journal of the American Chemical Society·Savka I StoevaChad A Mirkin
Aug 15, 2006·Inorganic Chemistry·Xun WangYadong Li
Sep 21, 2006·Journal of the American Chemical Society·Guodong LiuYuehe Lin
Sep 21, 2006·Journal of the American Chemical Society·Peng ZhangDamon Wheeler
Oct 20, 2006·The Journal of Physical Chemistry. B·Paresh Chandra RayGopala Krishna Darbha
Nov 15, 2006·Lab on a Chip·Edgar D GoluchChang Liu

❮ Previous
Next ❯

Citations

Oct 28, 2016·Biotechnology Journal·Laura SutarlieXiaodi Su
Sep 27, 2019·Nanoscale·Roger M PallaresXiaodi Su
Mar 10, 2020·Research : a Science Partner Journal·Xiaodi SuXian Jun Loh
Nov 11, 2020·Chemistry, an Asian Journal·Xiaodi SuXian Jun Loh
Apr 4, 2021·Sensors·Ricardo Matias TrujilloRossana Elena Madrid
May 4, 2021·Frontiers in Chemistry·Mindy Levine
Jan 24, 2020·Inorganic Chemistry·Roger M PallaresRebecca J Abergel
Aug 24, 2021·Chemistry, an Asian Journal·Laura SutarlieXiaodi Su

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.