Nanomaterials for Treating Bacterial Biofilms on Implantable Medical Devices

Nanomaterials
Hoai My TranPhong A Tran

Abstract

Bacterial biofilms are involved in most device-associated infections and remain a challenge for modern medicine. One major approach to addressing this problem is to prevent the formation of biofilms using novel antimicrobial materials, device surface modification or local drug delivery; however, successful preventive measures are still extremely limited. The other approach is concerned with treating biofilms that have already formed on the devices; this approach is the focus of our manuscript. Treating biofilms associated with medical devices has unique challenges due to the biofilm's extracellular polymer substance (EPS) and the biofilm bacteria's resistance to most conventional antimicrobial agents. The treatment is further complicated by the fact that the treatment must be suitable for applying on devices surrounded by host tissue in many cases. Nanomaterials have been extensively investigated for preventing biofilm formation on medical devices, yet their applications in treating bacterial biofilm remains to be further investigated due to the fact that treating the biofilm bacteria and destroying the EPS are much more challenging than preventing adhesion of planktonic bacteria or inhibiting their surface colonization. In thi...Continue Reading

References

Mar 1, 1994·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E P DellingerR P Wenzel
Apr 29, 1999·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·A J MangramW R Jarvis
Apr 11, 2001·Emerging Infectious Diseases·R M Donlan
Sep 21, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R M Donlan
Mar 24, 2004·International Journal of Antimicrobial Agents·Peter TenkeElisabeth Nagy
Mar 26, 2004·Nature Reviews. Microbiology·Luanne Hall-StoodleyPaul Stoodley
Jul 13, 2006·Journal of Controlled Release : Official Journal of the Controlled Release Society·Hongtao LvJie Yan
Aug 29, 2006·Chemical Society Reviews·Evan M Hetrick, Mark H Schoenfisch
Nov 3, 2006·The Journal of Bone and Joint Surgery. American Volume·William A JiranekA Seth Greenwald
Feb 29, 2008·The Journal of Antimicrobial Chemotherapy·David RoeJean-Baptiste Roullet
Mar 28, 2008·Biotechnology and Bioengineering·James D Bryers
Jul 26, 2008·Nature Nanotechnology·Lizeng GaoXiyun Yan
Dec 17, 2008·Journal of Bacteriology·David G Davies, Cláudia N H Marques
May 19, 2010·Journal of Endodontics·Annie ShresthaAnil Kishen
Aug 3, 2010·Nature Reviews. Microbiology·Hans-Curt Flemming, Jost Wingender
Jul 23, 2011·Virulence·Ruijie HuangRichard L Gregory
Jan 1, 2010·Journal of Nanoparticle Research : an Interdisciplinary Forum for Nanoscale Science and Technology·Christian VilliersPatrice Marche
Nov 30, 2011·MRS Bulletin·Lars D Renner, Douglas B Weibel
Feb 9, 2012·Chemical Society Reviews·Rubul MoutVincent M Rotello
Apr 21, 2012·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Nhiem Tran, Phong A Tran
May 24, 2012·Applied Microbiology and Biotechnology·Kateryna BazakaElena P Ivanova
Jun 8, 2012·The Journal of Trauma and Acute Care Surgery·Benjamin JohnsonPhilip J Roberts
Aug 1, 2012·Proceedings of the National Academy of Sciences of the United States of America·Alexander K EpsteinJoanna Aizenberg
Aug 14, 2012·Chemical Society Reviews·Sangram Keshari SamalPeter Dubruel
Sep 29, 2012·Science Translational Medicine·Henk J BusscherDavid W Grainger
Mar 7, 2013·Surgical Infections·Dale W BratzlerUNKNOWN Society for Healthcare Epidemiology of America (SHEA)
Sep 7, 2013·ACS Applied Materials & Interfaces·Danielle L SlombergMark H Schoenfisch
Nov 10, 2013·Nanomedicine : Nanotechnology, Biology, and Medicine·Annie ShresthaAnil Kishen
May 6, 2014·Journal of Controlled Release : Official Journal of the Controlled Release Society·Katrien ForierKevin Braeckmans
Aug 29, 2014·BioMed Research International·Manzoor Ahmad GatooSwaleha Zubair
Apr 8, 2015·Food Microbiology·Md Furkanur Rahaman MizanSang-Do Ha
Apr 29, 2015·Journal of Controlled Release : Official Journal of the Controlled Release Society·Aida BaeloEduard Torrents
Jun 18, 2015·ACS Nano·Bradley DuncanVincent M Rotello
Dec 15, 2015·Scientific Reports·Divya Prakash GnanadhasDipshikha Chakravortty
Jan 6, 2016·Scientific Reports·Haibo MuJinyou Duan
Feb 4, 2016·Materials Science & Engineering. C, Materials for Biological Applications·S Ferraris, S Spriano
Feb 11, 2016·The Biochemical Journal·Heidi Abrahamse, Michael R Hamblin
May 14, 2016·Infection and Drug Resistance·Chase M WattersNancy J Millenbaugh
May 28, 2016·Pharmaceutics·Zora Rukavina, Željka Vanić

❮ Previous
Next ❯

Citations

Feb 13, 2021·Antibiotics·Christian KranjecDzung B Diep
Feb 23, 2021·Journal of Basic Microbiology·Muzamil A RatherManabendra Mandal
Mar 16, 2021·Frontiers in Microbiology·Dibyajit LahiriRina Rani Ray
May 19, 2021·Critical Reviews in Microbiology·Fazlurrahman KhanYoung-Mog Kim
Jul 3, 2021·Nanomaterials·Francisco G BlancoM Auxiliadora Prieto

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

Related Papers

International Journal of Molecular Sciences
Qing Wei, Luyan Z Ma
Current Opinion in Otolaryngology & Head and Neck Surgery
J Christopher PostGarth D Ehrlich
Journal of Microbiology and Biotechnology
Keehoon Lee, Sang Sun Yoon
Enfermedades infecciosas y microbiología clínica
José Manuel Rodríguez-Martínez, Alvaro Pascual
© 2021 Meta ULC. All rights reserved