Nanoparticle-Based Wound Dressing: Recent Progress in the Detection and Therapy of Bacterial Infections.

Bioconjugate Chemistry
Chen XuAiguo Wu

Abstract

Bacterial infections in wounds often delay the healing process, and may seriously threaten human life. It is urgent to develop wound dressings to effectively detect and treat bacterial infections. Nanoparticles have been extensively used in wound dressings because of their specific properties. This review highlights the recent progress on nanoparticle-based wound dressings for bacterial detection and therapy. Specifically, nanoparticles have been applied as intrinsic antibacterial agents or drug delivery vehicles to treat bacteria in wounds. Moreover, nanoparticles with photothermal or photodynamic property have also been explored to endow wound dressings with significant optical properties to further enhance their bactericidal effect. More interestingly, nanoparticle-based smart dressings have been recently explored for bacteria detection and treatment, which enables an accurate assessment of bacterial infection and a more precise control of on-demand therapy.

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Citations

Oct 12, 2020·Journal of Pharmaceutical Sciences·Tracey Anastacia JecksonBapi Gorain
May 5, 2021·ACS Applied Materials & Interfaces·Taylor WrightMichael O Wolf
Jan 4, 2022·ACS Applied Materials & Interfaces·Taylor WrightMichael O Wolf
Nov 23, 2021·Angewandte Chemie·Sorour DarvishiIoanna Mela

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