Nanoparticles Actively Fragment Armored Droplets

ACS Nano
François SicardAlberto Striolo

Abstract

Understanding the complexity of fragmentation processes is essential for regulating intercellular communication in mechanistic biology and developing bottom-up approaches in a large range of multiphase flow processes. In this context, self-fragmentation proceeds without any external mechanical energy input, allowing one to create efficiently micro- and nanodroplets. Here we examine self-fragmentation in emulsion nanodroplets stabilized by solid particles with different surface features. Mesoscopic modeling and accelerated dynamics simulations allow us to overcome the limitations of atomistic simulations and offer detailed insight into the interplay between the evolution of the droplet shape and the particle finite-size effects at the interface. We show that finite-size nanoparticles play an active role in the necking breakup, behaving like nanoscale razors, and affect strongly the thermodynamic properties of the system. The role played by the particles during self-fragmentation might be of relevance to multifunctional biomaterial design and tuning of signaling pathways in mechanistic biology.

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Citations

Mar 11, 2020·Journal of Colloid and Interface Science·Daniel J Arismendi-Arrieta, Angel J Moreno
Mar 18, 2021·Journal of Chemical Theory and Computation·François SicardEdina Rosta
Jul 16, 2021·ACS Nano·François Sicard, Jhoan Toro-Mendoza
Aug 15, 2019·Journal of Chemical Theory and Computation·Abeer Khedr, Alberto Striolo

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