Nanoparticles for the Treatment of Wounds

Current Pharmaceutical Design
Felipe Oyarzun-AmpueroI Moreno-Villoslada

Abstract

The treatment of skin wounds represents an important research area due to the important physiological and aesthetic role of this tissue. During the last years, nanoparticles have emerged as important platforms to treat skin wounds. Silver, gold, and copper nanoparticles, as well as titanium and zinc oxide nanoparticles, have shown potential therapeutic effects on wound healing. Due to their specific characteristics, nanoparticles such as nanocapsules, polymersomes, solid lipid nanoparticles, and polymeric nanocomplexes are ideal vehicles to improve the effect of drugs (antibiotics, growth factors, etc.) aimed at wound healing. On the other hand, if active excipients are added during the formulation, such as hyaluronate or chitosan, the nanomedicine could significantly improve its potential. In addition, the inclusion of nanoparticles in different pharmaceutical materials may enhance the beneficial effects of the formulations, and allow achieving a better dose control. This paper aims at reviewing significant findings in the area of nanoparticles and wound treatment. Among the reviewed topics, we underline formulations comprising inorganic, polymeric, surfactant self-assembled, and lipid nanosystems. Among the drugs included in ...Continue Reading

Citations

Jul 12, 2016·Electromagnetic Biology and Medicine·Christina L RossBenjamin S Harrison
Feb 10, 2018·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Miguel ConchaSandra L Orellana
Jul 6, 2018·Drug Development and Industrial Pharmacy·Ujjawal BairagiBrahmeshwar Mishra
Jan 29, 2019·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Rubbel SinglaAmitabha Acharya
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Mar 29, 2018·Applied Microbiology and Biotechnology·Muhammad OvaisZabta Khan Shinwari
May 11, 2017·Frontiers in Immunology·Martin HimlyAlbert Duschl
Jul 3, 2020·Current Pharmaceutical Design·Venkateshwaran KrishnaswamiRuckmani Kandasamy
Jun 11, 2020·Current Pharmaceutical Design·Phui Qi NgDinesh Kumar Chellappan
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