Nanoscale Self-Assembly for Therapeutic Delivery

Frontiers in Bioengineering and Biotechnology
Santosh YadavPradeep Kumar

Abstract

Self-assembly is the process of association of individual units of a material into highly arranged/ordered structures/patterns. It imparts unique properties to both inorganic and organic structures, so generated, via non-covalent interactions. Currently, self-assembled nanomaterials are finding a wide variety of applications in the area of nanotechnology, imaging techniques, biosensors, biomedical sciences, etc., due to its simplicity, spontaneity, scalability, versatility, and inexpensiveness. Self-assembly of amphiphiles into nanostructures (micelles, vesicles, and hydrogels) happens due to various physical interactions. Recent advancements in the area of drug delivery have opened up newer avenues to develop novel drug delivery systems (DDSs) and self-assembled nanostructures have shown their tremendous potential to be used as facile and efficient materials for this purpose. The main objective of the projected review is to provide readers a concise and straightforward knowledge of basic concepts of supramolecular self-assembly process and how these highly functionalized and efficient nanomaterials can be useful in biomedical applications. Approaches for the self-assembly have been discussed for the fabrication of nanostructur...Continue Reading

References

Sep 1, 1993·Bioconjugate Chemistry·J Haensler, F C Szoka
Jul 17, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D W NorthfeltD H Henry
Jun 7, 2000·Proceedings of the National Academy of Sciences of the United States of America·T C HolmesS Zhang
Jan 5, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Ehud Gazit
Apr 4, 2002·Proceedings of the National Academy of Sciences of the United States of America·Sylvain VautheyShuguang Zhang
Apr 18, 2002·Proceedings of the National Academy of Sciences of the United States of America·George M Whitesides, Mila Boncheva
Apr 26, 2003·Science·Meital Reches, Ehud Gazit
Jun 3, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Tae-You KimYung-Jue Bang
Dec 9, 2004·Chemical Reviews·M N V Ravi KumarA J Domb
May 12, 2005·The Journal of Clinical Endocrinology and Metabolism·Pamela U FredaDaniel Rabinowitz
Jul 20, 2005·Anti-cancer Drugs·Ralf-Dieter HofheinzAndreas Hochhaus
May 16, 2006·Proceedings of the National Academy of Sciences of the United States of America·Michael E DavisRichard T Lee
Nov 1, 2006·Critical Reviews in Oncology/hematology·T M H NiersD J Richel
Mar 27, 2007·Journal of Controlled Release : Official Journal of the Controlled Release Society·Tommasina CovielloFranco Alhaique
Dec 20, 2007·The Journal of Physical Chemistry. B·Stefan TsonchevSamuel I Stupp
Apr 4, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Vicki M Tysseling-MattiaceJohn A Kessler
Aug 15, 2008·Cancer Research·Zhuang LiuHongjie Dai
Sep 27, 2008·Journal of Controlled Release : Official Journal of the Controlled Release Society·Allan S Hoffman
Feb 25, 2009·Expert Opinion on Pharmacotherapy·Ronnie T P Poon, Nicholas Borys
Feb 18, 2010·Journal of Chemical Theory and Computation·Steven E Wheeler, K N Houk
Mar 30, 2010·Journal of Medicinal Chemistry·Caterina BissantzMartin Stahl
Apr 27, 2010·Chemical Society Reviews·Roberto J BreaJuan R Granja
Aug 13, 2011·Organic & Biomolecular Chemistry·Jishu NaskarArindam Banerjee
Aug 23, 2011·Chemical Communications : Chem Comm·Jin Woo BaeSeungpyo Hong
Nov 3, 2011·ACS Nano·Stephen SoukaseneSamuel I Stupp
Feb 23, 2012·Journal of Controlled Release : Official Journal of the Controlled Release Society·Fabienne DanhierVéronique Préat
Apr 12, 2012·Molecular BioSystems·Manohar MahatoAshwani Kumar Sharma
May 30, 2012·Current Drug Delivery·Gemma VilarFernando Albericio
Jun 5, 2012·Nature Nanotechnology·Hyukjin LeeDaniel G Anderson
Jun 9, 2012·Chemical Society Reviews·Lauren E Buerkle, Stuart J Rowan
Jun 16, 2012·Chemical Reviews·N Mariano CorreaNancy E Levinger
Jul 19, 2012·Journal of the American Chemical Society·Qiao JiangBaoquan Ding
Sep 7, 2012·ACS Nano·Yong-Xing ZhaoBjörn Högberg
Jan 1, 2013·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Esmaiel JabbariXuezhong He
Jan 8, 2013·ACS Nano·Mariarosa MazzaIjeoma F Uchegbu
Jan 25, 2013·International Journal of Molecular Sciences·Sachiko Kaihara Nitta, Keiji Numata
Jan 29, 2013·ACS Macro Letters·Ryan M PearsonSeungpyo Hong
Apr 3, 2013·Chemical Society Reviews·Zonglin ChuYujun Feng
May 1, 2013·Proceedings of the National Academy of Sciences of the United States of America·Guizhi ZhuWeihong Tan

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Citations

Aug 6, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Shabnam TarvirdipourCornelia G Palivan
Oct 6, 2020·Frontiers in Pharmacology·Enrico LattuadaPatrizia Filetici
Sep 5, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Adriana Aurelia ChisAdina Frum
Oct 13, 2020·Journal of Controlled Release : Official Journal of the Controlled Release Society·Sena KaraosmanogluXianfeng Chen
Feb 26, 2021·Current Opinion in Chemical Biology·Xiaomin JiangWenbin Lin
Apr 4, 2021·International Journal of Molecular Sciences·Piotr Tarach, Anna Janaszewska
Apr 9, 2021·Advanced Drug Delivery Reviews·Sedigheh BorandehJukka Seppälä
Jun 3, 2021·Polymers·Jakub ŁagiewkaWojciech Ciesielski
Jun 1, 2021·Frontiers in Chemistry·M Mustafa MamunEric P Vejerano
Jul 31, 2021·International Journal of Nanomedicine·Jun-Young ParkDongwoo Khang
Aug 8, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Nicola MicaleAntonio Speciale
Aug 10, 2021·Frontiers in Molecular Biosciences·Yun HaoLuo Zhang
Aug 17, 2021·Frontiers in Chemistry·Andrew FaganSilvia Giordani
Oct 26, 2021·ChemPlusChem·Diptiprava SahooSoumen De
Oct 27, 2021·The Journal of Physical Chemistry. B·Youngbeom JoSeokmin Shin

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Methods Mentioned

BETA
PISA
transfection
X-ray

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