Nanoscale Surface Charge Visualization of Human Hair

Analytical Chemistry
Faduma M MaddarPatrick R Unwin

Abstract

The surface charge and topography of human hair are visualized synchronously at the nanoscale using scanning ion conductance microscopy (SICM), a scanning nanopipette probe technique that uses local ion conductance currents to image the physicochemical properties of interfaces. By combining SICM data with finite element method (FEM) simulations that solve for ion transport at the nanopipette under bias, one is able to quantitatively correlate colocated surface charge and topography. The hair samples studied herein, from a 25-year-old Caucasian male with light hair (as an exemplar), reveal that untreated hair, in areas ca. 1 cm from the root, has a fairly uniform negative charge density of ca. -15 mC/cm-2 (in pH 6.8 aqueous solution), with some higher magnitude negative values localized near the boundaries between hair cuticles. Common chemical treatments result in varying degrees of charge heterogeneity. A bleach treatment produces some highly negatively charged localized regions (-80 to -100 mC/cm-2 at pH 6.8), due to hair damage, while a chemical conditioner treatment causes an overall increase in the homogeneity of the surface charge, together with a shift in the surface charge to positive values. Bleached surfaces are tempo...Continue Reading

References

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Citations

May 20, 2020·Analytical and Bioanalytical Chemistry·Ran ChenMei Shen
Mar 11, 2021·Advances in Colloid and Interface Science·Gustavo S LuengoAndrew J Greaves
Dec 10, 2020·Chemical Reviews·Cheng ZhuLane A Baker
Feb 4, 2022·Soft Matter·Erik WeiandDaniele Dini

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