Nanostructured cupric oxide electrode: An alternative to amperometric detection of carbohydrates in anion-exchange chromatography

Analytica Chimica Acta
José T C Barragan, Lauro T Kubota

Abstract

In this paper, a new and low cost copper/cupric oxide nanostructured electrode is presented as an alternative to the amperometric detection of carbohydrates in high-performance anion exchange chromatography. The modified copper electrodes were prepared by a simple and fast method which resulted in the obtainment of homogeneously distributed nanostructures adhered to the surface with controlled chemical nature. The results, when compared to conventional copper electrodes, exhibited considerable improvements in analytical results, including: 1) Better repeatability in consecutive glucose detections, in which the percent relative standard deviation improved from 15.1% to 0.279%. 2) Significant improvements in the stability of the baseline and a decrease of the stabilization time, going from several hours to approximately 15 min. 3) Considerable increase in the sensitivity towards glucose, from 5.02 nA min mg L(-1) to 25.5 nA min mg L(-1). 4) Improvements in the detectability with limits as low as 1.09 pmol. 5) Wide working range of concentrations (1 × 10(-2) to 1 × 10(4) mg L(-1)). 6) Good linearity with correlation coefficients greater than 0.998. 7) Possibility of detecting different molecules of carbohydrates (lactose, maltose,...Continue Reading

References

Feb 6, 2004·Nature Reviews. Drug Discovery·Eric Schmidt, Rod Wong
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Mar 1, 2012·Angewandte Chemie·Agnieszka M RuppertRegina Palkovits
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Feb 28, 2015·ACS Applied Materials & Interfaces·Wei-Ning WangPratim Biswas

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Citations

Sep 30, 2016·Water Science and Technology : a Journal of the International Association on Water Pollution Research·Ali AzariKiomars Sharafi
Jun 26, 2021·Dalton Transactions : an International Journal of Inorganic Chemistry·Xuejuan XuYan Xu

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