Nanostructured Lipid-Based Delivery Systems as a Strategy to Increase Functionality of Bioactive Compounds

Ariadna Gasa-FalconOlga Martín-Belloso


Acquisition of a healthy lifestyle through diet has driven the food manufacturing industry to produce new food products with high nutritional quality. In this sense, consumption of bioactive compounds has been associated with a decreased risk of suffering chronic diseases. Nonetheless, due to their low solubility in aqueous matrices, high instability in food products during processing and preparation as well as poor bioavailability, the use of such compounds is sometimes limited. Recent advancements in encapsulation and protection of bioactive compounds has opened new possibilities for the development of novel food products. In this direction, the present review is attempting to describe encapsulation achievements, with special attention to nanostructured lipid-based delivery systems, i.e., nanoemulsions, multi-layer emulsions and liposomes. Functionality of bioactive compounds is directly associated with their bioavailability, which in turn is governed by several complex processes, including the passage through the gastrointestinal tract and transport to epithelial cells. Therefore, an overview of recent research on the properties of these nanostructured lipid-based delivery systems with a strong impact on the functionality of...Continue Reading


Mar 14, 2000·The Journal of Pharmacy and Pharmacology·D DimitrijevicA T Florence
Nov 4, 2005·Chemistry and Physics of Lipids·Paola PalozzaNevio Picci
Dec 24, 2005·Critical Reviews in Food Science and Nutrition·T Matthew TaylorJochen Weiss
Dec 29, 2005·Journal of Medicinal Food·S XianquanJ Yueming
Dec 7, 2006·Journal of Agricultural and Food Chemistry·Henelyta S RibeiroHelmar Schubert
Jan 16, 2007·Advances in Colloid and Interface Science·Demet Guzey, D Julian McClements
Apr 15, 2008·Current Opinion in Biotechnology·Birgit Holst, Gary Williamson
Jan 1, 2009·Progress in Lipid Research·Harjinder SinghDavid Horne
May 18, 2010·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Yan LiDavid Julian McClements
Jun 10, 2010·Journal of Agricultural and Food Chemistry·Venkateshwarlu GudipatiEric Andrew Decker
Jun 15, 2010·Critical Reviews in Food Science and Nutrition·Caitlin S BoonEric A Decker
Aug 17, 2010·Journal of Agricultural and Food Chemistry·Tanushree TokleDavid Julian McClements
Dec 8, 2010·Journal of Agricultural and Food Chemistry·Sung Je LeeDavid Julian McClements
Jan 18, 2011·Advances in Colloid and Interface Science·Julia Maldonado-ValderramaAlan Mackie
Dec 14, 2011·Journal of Agricultural and Food Chemistry·Xiaoqing YangQingrong Huang
Jul 31, 2012·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Zoltán UjhelyiIldikó Bácskay
Sep 8, 2012·Food Chemistry·Cheng QianDavid Julian McClements
Jan 22, 2013·Journal of Agricultural and Food Chemistry·Rong LiangQingrong Huang
Jun 4, 2013·International Journal of Pharmaceutics·Hakon H SigurdssonClaus-Michael Lehr
Jun 11, 2014·Critical Reviews in Food Science and Nutrition·S RajarathnamS Rajarathnam
Sep 17, 2014·Critical Reviews in Food Science and Nutrition·Arantxa Rodriguez-Casado
Dec 3, 2014·Colloids and Surfaces. B, Biointerfaces·Chen TanShuqin Xia
Apr 17, 2015·Journal of Agricultural and Food Chemistry·Ruth ClarkSeong-Ho Lee
Aug 8, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Xing ChenCheng-Mei Liu
Jan 27, 2017·Annual Review of Food Science and Technology·David Julian McClementsCheryl Chung
Apr 8, 2017·International Journal of Biological Macromolecules·Ping ShaoPeilong Sun
May 4, 2017·Drug Delivery and Translational Research·Tanmoy SadhukhaSwayam Prabha

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