Nanostructured Lipid-Based Delivery Systems as a Strategy to Increase Functionality of Bioactive Compounds

Foods
Ariadna Gasa-FalconOlga Martín-Belloso

Abstract

Acquisition of a healthy lifestyle through diet has driven the food manufacturing industry to produce new food products with high nutritional quality. In this sense, consumption of bioactive compounds has been associated with a decreased risk of suffering chronic diseases. Nonetheless, due to their low solubility in aqueous matrices, high instability in food products during processing and preparation as well as poor bioavailability, the use of such compounds is sometimes limited. Recent advancements in encapsulation and protection of bioactive compounds has opened new possibilities for the development of novel food products. In this direction, the present review is attempting to describe encapsulation achievements, with special attention to nanostructured lipid-based delivery systems, i.e., nanoemulsions, multi-layer emulsions and liposomes. Functionality of bioactive compounds is directly associated with their bioavailability, which in turn is governed by several complex processes, including the passage through the gastrointestinal tract and transport to epithelial cells. Therefore, an overview of recent research on the properties of these nanostructured lipid-based delivery systems with a strong impact on the functionality of...Continue Reading

References

Mar 14, 2000·The Journal of Pharmacy and Pharmacology·D DimitrijevicA T Florence
Nov 4, 2005·Chemistry and Physics of Lipids·Paola PalozzaNevio Picci
Dec 24, 2005·Critical Reviews in Food Science and Nutrition·T Matthew TaylorJochen Weiss
Dec 29, 2005·Journal of Medicinal Food·S XianquanJ Yueming
Dec 7, 2006·Journal of Agricultural and Food Chemistry·Henelyta S RibeiroHelmar Schubert
Jan 16, 2007·Advances in Colloid and Interface Science·Demet Guzey, D Julian McClements
Apr 15, 2008·Current Opinion in Biotechnology·Birgit Holst, Gary Williamson
Jan 1, 2009·Progress in Lipid Research·Harjinder SinghDavid Horne
May 18, 2010·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Yan LiDavid Julian McClements
Jun 10, 2010·Journal of Agricultural and Food Chemistry·Venkateshwarlu GudipatiEric Andrew Decker
Jun 15, 2010·Critical Reviews in Food Science and Nutrition·Caitlin S BoonEric A Decker
Aug 17, 2010·Journal of Agricultural and Food Chemistry·Tanushree TokleDavid Julian McClements
Dec 8, 2010·Journal of Agricultural and Food Chemistry·Sung Je LeeDavid Julian McClements
Jan 18, 2011·Advances in Colloid and Interface Science·Julia Maldonado-ValderramaAlan Mackie
Dec 14, 2011·Journal of Agricultural and Food Chemistry·Xiaoqing YangQingrong Huang
Jul 31, 2012·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Zoltán UjhelyiIldikó Bácskay
Sep 8, 2012·Food Chemistry·Cheng QianDavid Julian McClements
Jan 22, 2013·Journal of Agricultural and Food Chemistry·Rong LiangQingrong Huang
Jun 4, 2013·International Journal of Pharmaceutics·Hakon H SigurdssonClaus-Michael Lehr
Jun 11, 2014·Critical Reviews in Food Science and Nutrition·S RajarathnamS Rajarathnam
Sep 17, 2014·Critical Reviews in Food Science and Nutrition·Arantxa Rodriguez-Casado
Dec 3, 2014·Colloids and Surfaces. B, Biointerfaces·Chen TanShuqin Xia
Apr 17, 2015·Journal of Agricultural and Food Chemistry·Ruth ClarkSeong-Ho Lee
Aug 8, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Xing ChenCheng-Mei Liu
Jan 27, 2017·Annual Review of Food Science and Technology·David Julian McClementsCheryl Chung
Apr 8, 2017·International Journal of Biological Macromolecules·Ping ShaoPeilong Sun
May 4, 2017·Drug Delivery and Translational Research·Tanmoy SadhukhaSwayam Prabha

❮ Previous
Next ❯

Citations

Sep 25, 2020·3 Biotech·Farzad RahmatiMehrnaz Hatami
Mar 20, 2021·Analytica Chimica Acta·Gertrud E MorlockSabrina Brinkmann
Mar 30, 2021·Critical Reviews in Food Science and Nutrition·Talita A ComunianAndré Brodkorb
Apr 4, 2021·Antioxidants·Vaibhav Kumar MauryaSunil Pareek

❮ Previous
Next ❯

Methods Mentioned

BETA
membrane filtration
in

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Epigenetics Insights from Twin Studies

Find the latest research on epigenetics and twin studies here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.