Nanotechnology as a Promising Strategy for Anticancer Drug Delivery

Current Drug Delivery
Mona Basha

Abstract

Cancer was and still a very stressful and urgent disease condition representing a leading cause of death in developed as well as developing countries. Although, much research work in both medical and pharmaceutical fields has evolved in the past few years in addition to some promising clinical trials and few market products, cancer becomes much wilder, threatening and getting more lives. Most approaches have focused on the synthesis of new active ingredients or chemical modification of available ones, formulating them in suitable dosage forms aiming for targeted and effective drug delivery with minimal side effects. Recently, application of nanotechnology through formulation of nanocarriers has acquired much more attention in treating different types of cancer tumors. Being explored in cancer therapy, nanocarriers have shown a promising capability to enhance intracellular uptake of active agents, promoting their accumulation in the tumor mass in addition to the reduction of the cellular toxicity compared to conventional chemotherapeutics. In view of the above findings, this review discusses recent advances in nanotechnology-based carriers for cancer drug delivery, providing detailed description of different nanocarriers from hi...Continue Reading

Citations

Jul 30, 2021·Advanced Drug Delivery Reviews·Xiaoyu XuHongbo Zhang
Feb 5, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Arunendra Saha RayMarie-Christine Daniel
Dec 5, 2021·Journal of Materials Science. Materials in Medicine·Mahmood BaraniFrancesco Baino

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