Nanotransporters for drug delivery

Current Opinion in Biotechnology
Tessa Lühmann, Lorenz Meinel

Abstract

Soluble nanotransporters for drugs can be profiled for targeted delivery particularly to maximize the efficacy of highly potent drugs while minimizing off target effects. This article outlines on the use of biological carrier molecules with a focus on albumin, various drug linkers for site specific release of the drug payload from the nanotransporter and strategies to combine these in various ways to meet different drug delivery demands particularly the optimization of the payload per nanotransporter.

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Citations

Feb 27, 2017·Colloids and Surfaces. B, Biointerfaces·Lijun LiangQi Wang
Dec 6, 2018·Nanoscale Research Letters·Federica RinaldiMaria Carafa
Dec 25, 2019·International Journal of Pharmaceutics·Mahboobeh JafariAli Mohammad Tamaddon
Jan 23, 2021·RSC Medicinal Chemistry·Ekaterina S SazanovaAlexey Yu Fedorov
Jul 11, 2021·Journal of Controlled Release : Official Journal of the Controlled Release Society·Imke Rudnik-Jansen, Kenneth A Howard
Mar 13, 2017·ACS Biomaterials Science & Engineering·Tessa LühmannLorenz Meinel

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