NAPSI utilization as an evaluation method of nail psoriasis in patients using acitretin

Anais Brasileiros De Dermatologia
Maira Mitsue MukaiJosé Hermênio Cavalcante Lima Filho

Abstract

assessment instruments of nail psoriasis have been published in literature as means to standardize the previous subjective assessments of authors. Using Nail Psoriasis Severity Index for evaluation in patients with plaque psoriasis during treatment with acitretin. Thirty volunteers with plaque psoriasis were selected for the study. Twenty patients (8 women and 12 men) completed the study. The initial dose of acitretin was 0.3 mg/kg/day for 30 days and was later raised to 0.5 mg/kg/day. Nail Psoriasis Severity Index was collected in the first evaluation, after 2 and 4 months. Nails of both hands were evaluated. nail lesions were present in all patients at first evaluation. The initial Nail Psoriasis Severity Index median was 20 and the final score 20.5 (2.5% of worsening at the end of the study). No statistically significant difference between the three evaluations was found (X2 = 0.8084, GL = 2, p = 0.6657). Seven patients worsened in the final score. Three patients improved 50% of the initial Nail Psoriasis Severity Index and only one had an improvement of 75%. Linear correlation showed a weak association between the improvement percentage in PASI and Nail Psoriasis Severity Index (r = 0.105, F = 2.12, p = 0.162). The method w...Continue Reading

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Citations

Oct 9, 2013·Dermatologic Therapy·Noelani E Gonzalez OrtizJeffrey M Weinberg
Jan 10, 2018·Pediatric Dermatology·Marjorie UberBetina Werner
Apr 29, 2014·Anais Brasileiros De Dermatologia·Karen Regina Rosso SchonsOdirlei André Monticielo
Jul 2, 2015·Anais Brasileiros De Dermatologia·Karen Regina Rosso SchonsOdirlei André Monticielo
Jun 14, 2013·Dermatology Research and Practice·Yasemin Oram, A Deniz Akkaya
Oct 10, 2012·Anais Brasileiros De Dermatologia·Ana Maria Tchornobay
Oct 27, 2017·Indian Journal of Dermatology, Venereology and Leprology·Salma Samir Omar, Hany Ahmed Helaly
Mar 23, 2021·Dermatologic Clinics·Jose W Ricardo, Shari R Lipner
Jun 3, 2021·Revista da Associação Médica Brasileira·Júlia Amanda Guzatti ValdugaThelma Larocca Skare
Jun 24, 2021·Revista da Associação Médica Brasileira·Júlia Amanda Guzatti ValdugaThelma Larocca Skare
Jul 31, 2013·Actas dermo-sifiliográficas·G CarreteroUNKNOWN Psoriasis Group of the AEDV

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