Narrow band imaging evaluation of duodenal villi in patients with and without celiac disease: A prospective study

World Journal of Gastrointestinal Endoscopy
James H TabibianChristopher J Gostout

Abstract

Duodenal biopsies are commonly obtained during esophagogastroduodenoscopy (EGD) but are very often histopathologically normal. Therefore, a more strategic method for evaluating the duodenal mucosa and avoiding unnecessary biopsies is needed. To examine the clinical utility of narrow band imaging (NBI) for evaluating duodenal villous morphology. We performed a prospective cohort study of adult patients at Mayo Clinic Rochester from 2013-2014 who were referred for EGD with duodenal biopsies. A staff endoscopist scored, in real-time, the NBI-based appearance of duodenal villi into one of three categories (normal, partial villous atrophy, or complete villous atrophy), captured ≥ 2 representative duodenal NBI images, and obtained mucosal biopsies therein. Images were then scored by an advanced endoscopist and gastroenterology fellow, and biopsies (gold standard) by a pathologist, in a masked fashion using the same three-category classification. Performing endoscopist, advanced endoscopist, and fellow NBI scores were compared to histopathology to calculate performance characteristics [sensitivity, specificity, positive and negative, negative predictive value (NPV), and accuracy]. Inter-rater agreement was assessed with Cohen's kappa....Continue Reading

References

Sep 23, 2003·The American Journal of Gastroenterology·Sanjay KakarLawrence J Burgart
Jan 28, 2004·Gastrointestinal Endoscopy·Tatsuya YoshidaShin-ei Kudo
Jun 11, 2004·Journal of Biomedical Optics·Kazuhiro GonoTakao Endo
Jul 25, 2006·Gastrointestinal Endoscopy·Gregory G Ginsberg
Jun 5, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Gino Roberto CorazzaFrancesco Donato
May 24, 2011·Gastrointestinal Endoscopy·Benjamin LebwohlRobert M Genta
Aug 14, 2012·Gastroenterology·Anne F PeeryNicholas J Shaheen
Jan 31, 2014·Endoscopy·Kassem BaradaPeter H Green
Mar 31, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Janie J YangBenjamin Lebwohl
Sep 4, 2015·Gastroenterology·Anne F PeeryRobert S Sandler
Feb 3, 2016·Gastroenterology·Peter D MooneyDavid S Sanders
Mar 21, 2016·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Hugo A PennyDavid S Sanders

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Citations

Jul 23, 2020·Revista da Associação Médica Brasileira·Seval AkayHarun Akar

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Methods Mentioned

BETA
biopsies
sedation
biopsy

Software Mentioned

JMP

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