Narrow Band Imaging-guided resection of oral cavity cancer decreases local recurrence and increases survival

Oral Diseases
Camile S Farah

Abstract

Overall local recurrence of oral squamous cell carcinoma (OSCC) is estimated at 20%. Incomplete primary tumour excision contributes to localised postsurgical recurrence of OSCC. The purpose of this study was to report on patient outcomes following resection of OSCC using Narrow Band Imaging (NBI). Patients with OSCC requiring resection were visualised under conventional white light (WL) then NBI using an Olympus NBI ENF-VQ nasendoscope with CLV-180 light source and processor (Olympus Medical Systems, Tokyo, Japan). OSCC tissue was resected to the NBI-defined surgical margins, and patients followed for a minimum of 5 years postsurgery to assess local recurrence rate (LRR) and disease-free survival (DFS). Of the 20 patients recruited for this study, one patient (5%) declined follow-up. At the latest follow-up period (up to 7 years postsurgery), 14 of 19 patients (73.68%) were alive with no recurrence. Two patients (10.53%) had died from metastatic disease with no local recurrence, one patient (5.26%) had died from disease with local recurrence, and two patients (10.53%) had died disease-free from other causes. In total, 16 of 19 patients (84.21%) who were followed for a minimum of 5 years were still alive and had not developed lo...Continue Reading

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References

Mar 19, 2002·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·M WeijersI van der Waal
Jan 13, 2005·The American Journal of Surgical Pathology·Margaret Brandwein-GenslerBeverly Yiyao Wang
Dec 19, 2006·Oral Oncology·Abdulaziz BinahmedAhmed A Abdoh
Mar 25, 2008·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Akihito WatanabeShigeyuki Sasaki
Sep 23, 2008·Oral Oncology·Saman Warnakulasuriya
Nov 5, 2008·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Akihito WatanabeShigeyuki Sasaki
Feb 24, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Manabu MutoDaizo Saito
Jan 15, 2011·The British Journal of Oral & Maxillofacial Surgery·Neil C-W TanRoberto Puxeddu
Mar 31, 2011·British Journal of Cancer·P L FriedlandM Phillips
Sep 4, 2012·Head & Neck·Michael L HinniLeon Barnes
Sep 16, 2014·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayFreddie Bray
Feb 24, 2015·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Jose L López-Cedrún, Jesús Andrés de Llano
Feb 27, 2015·Oral Oncology·Caroline Rachael AndersonMarc Moncrieff
Jul 27, 2015·Photodiagnosis and Photodynamic Therapy·Zaid HamdoonColin Hopper
Apr 27, 2017·JAMA Otolaryngology-- Head & Neck Surgery·Kendall K TascheSteven M Sperry

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Citations

Mar 8, 2019·Current Opinion in Otolaryngology & Head and Neck Surgery·Giuditta MannelliCesare Piazza
Jun 10, 2019·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Katherine PollaersCamile S Farah
Nov 5, 2019·Oral Diseases·Gabriela Anaya-Saavedra
Aug 3, 2020·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Anjie MinTong Su
Oct 13, 2020·Endoscopy International Open·Maria Pia Costa-SantosPierre H Deprez
Dec 15, 2020·Surgical Oncology·Francesca Boscolo NataNicolò de Manzini
Mar 17, 2021·European Annals of Otorhinolaryngology, Head and Neck Diseases·E ChabrillacS Vergez
Mar 23, 2021·Surgical Innovation·Chi-Kuang Young, Shiang-Fu Huang
Mar 21, 2021·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Tongwu WangHongyu Yang

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