Narrowband UVB therapy as an effective treatment for Schamberg's disease

The Australasian Journal of Dermatology
Anita L Lasocki, Robert I Kelly

Abstract

A 33-year-old man presented with a 3-month history of a widespread pigmented purpuric eruption over his trunk and limbs. The clinical presentation and histology were consistent with a diagnosis of Schamberg's disease. The rash initially cleared following a short course of oral prednisolone at 25 mg daily for 3 weeks, which was weaned over the subsequent 4 weeks. Topical mometasone furoate ointment 0.1% daily was also applied to active areas. The rash recurred when prednisolone was reduced to below 5 mg per day. To prevent a further recurrence with weaning prednisolone, narrowband UVB therapy was commenced three times per week. The patient was continued on UV therapy over the next 5 months. The rash would flare after 2 to 3 weeks without treatment. The frequency of UV therapy was weaned and the patient remained clear on as little as one treatment every 2 weeks. Any further reduction, however, was associated with a recurrence. Narrowband UVB therapy should be considered for difficult or persistent cases of pigmented purpuric eruption.

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Citations

Nov 13, 2010·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Renée A D'AmbrosiaRichard G Glogau
Jan 21, 2009·Photodermatology, Photoimmunology & Photomedicine·Emek KocaturkSibel Sudogan
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Oct 29, 2020·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Diego Fernandez-NietoPablo Boixeda
Jan 4, 2020·Clinics in Dermatology·Alexa B Steuer, Jeffrey M Cohen
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