Nasal and paranasal esthesioneuroblastomas: clinical outcomes

European Annals of Otorhinolaryngology, Head and Neck Diseases
J MichelP Dessi

Abstract

Esthesioneuroblastomas (ENB) are rare tumours derived from the olfactory epithelium. Based on their experience and a review of the literature, the authors tried to identify the epidemiological, clinical, histological and therapeutic factors that influence overall and disease-free survival in their series of ENB. This retrospective study concerned eleven patients treated in a single institution for ENB of the nasal cavity and sinuses between 1978 and 2006. The data collected were submitted to statistical analysis using R 2.0(®) software. Overall survival and disease-free survival were estimated by the Kaplan-Meier method and prognostic factors were identified by Log-Rank test. This series comprised three women (27.2%) and eight men (72.8%) (sex ratio: 2.6). The mean age at diagnosis was 56 years (range: 37-69 years). No risk factors were identified in this cohort. The mean follow-up was 110.2 months (range: 7-348 months). This series included three T1 (27.3%), one T2 (9.1%), four T3 (36.3%) and three T4 (27.3%) tumours. The 1-year, 5-year and 10-year disease-free survival rates were 81.8%, 54.5% and 18.2%, and the corresponding overall survival rates were 100%, 90% and 60%, respectively. The main prognostic factors reported in t...Continue Reading

References

Nov 1, 1992·Head & Neck·R E Davis, M C Weissler
Aug 1, 1992·The Laryngoscope·P Dulguerov, T Calcaterra
Nov 15, 1993·International Journal of Radiation Oncology, Biology, Physics·R L FooteW M O'Fallon
May 1, 1993·Neurosurgery·A MoritaL M Quast
Aug 15, 2000·Head & Neck·V A RestoW H Westra
Mar 21, 2002·The Lancet Oncology·P DulguerovT C Calcaterra
Jan 17, 2003·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Peter IngeholmDorthe Francis
Jan 18, 2005·Head & Neck·Eduardo M DiazFranco DeMonte
Jul 19, 2005·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·S Kharoubi
Jan 11, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Maria SurianoAndrea Gallo
Mar 21, 2007·Archives of Otolaryngology--head & Neck Surgery·Daniel JethanamestDavid I Kutler
Sep 18, 2008·Head & Neck·Gideon BacharJonathan C Irish
May 16, 2009·The Laryngoscope·Anand K Devaiah, Michael T Andreoli
Oct 21, 2009·Archives of Otolaryngology--head & Neck Surgery·Mitchell R Gore, Adam M Zanation
Mar 17, 2010·International Journal of Radiation Oncology, Biology, Physics·Mahmut OzsahinAbderrahim Zouhair
Aug 14, 2010·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Adam M ZanationAnand K Devaiah
Feb 2, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sohrab SohrabiHeath B Mackley

❮ Previous
Next ❯

Citations

Nov 18, 2014·Acta Oto-laryngologica·Guillaume De BonnecazeSébastien Vergez
Jul 28, 2016·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·A LapierreS Yossi
Nov 14, 2013·The Journal of Craniofacial Surgery·Ali Cemal YumusakhuyluMurat Sari

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Incidence & Mortality

Cancer has emerged as a global concern due to its increase in incidence and mortality. Efforts are underway to evaluate and develop action plans to reduce the global burden of cancer. Currently, lung cancer, breast cancer and prostate cancer are the leading causes of cancer mortality. Here is the latest research on cancer incidence and mortality.