Abstract
When a patient presents with nasal obstruction a correct diagnosis must be made. Treatment may not always be required, and the need for intervention should be balanced against the risks of therapy. If the patient has an acute problem, such as the common cold or sinusitis, a topical decongestant may be the most immediately effective remedy, but this should never be continued for more than a few days and the patient should be warned against buying similar proprietary products. In more chronic cases, such as allergic or vasomotor rhinitis, or when decongestion of mucosa away from the nose (Eustachian tube) is required, oral treatment is best. A sympathomimetic administered orally (pseudoephedrine or phenylephrine) may be sufficient, or an antihistamine alone may be helpful in allergic rhinitis. Combination products are frequently effective, possibly more so than the individual ingredients, but when using such products the prescriber must remember the contraindications and precautions for each ingredient.
Citations
Mar 1, 1985·Journal of Ethnopharmacology·P A de Smet
Jan 1, 1994·Allergy·J BousquetF B Michel
Apr 1, 1988·Antimicrobial Agents and Chemotherapy·S J Sperber, F G Hayden
Nov 1, 1990·Respiratory Medicine·J BousquetF B Michel
Apr 16, 2004·Autonomic & Autacoid Pharmacology·M R CorbozJ A Hey
Aug 1, 1989·British Journal of Pharmacology·J S Lacroix, J M Lundberg
Jun 1, 1986·British Journal of Pharmacology·T L Berridge, A G Roach
Apr 17, 2004·The Medical Clinics of North America·Asher Qureshi, Teofilo Lee-Chiong
Aug 15, 1990·Biochemical Pharmacology·E G DelicadoD Aunis
Aug 13, 2015·Clinical Drug Investigation·Cathy K Gelotte, Brenda A Zimmerman
Jan 15, 2011·The Journal of Pharmacology and Experimental Therapeutics·Michel R CorbozJohn A Hey
May 23, 2001·Nutrition Reviews·H R Lieberman
Jul 6, 2019·Journal of Clinical Pharmacology·Cathy K GelotteValerie Gallagher
Jan 1, 1989·Pharmacotherapy·M E Dushay, C E Johnson
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Zeinab Breijyeh, Rafik Karaman