Nasal High-flow versus non-invasive ventilation in stable hypercapnic COPD: a preliminary report

Multidisciplinary Respiratory Medicine
Jens BräunlichHubert Wirtz

Abstract

There are no data available about effectiveness of Nasal High-flow (NHF)in chronic respiratory insufficiency. Eleven COPD patients with stable hypercapnia were adjusted to NHF-system with a flow of 20 l/min. After six weeks patients were switched to non-invasive ventilation (NIV) for another six weeks period. NHF led to significant decreases in resting pCO2. Between the devices we found no differences in pCO2 levels. NHF may thus be an alternative treatment device in stable hypercapnic COPD patients.

Associated Clinical Trials

References

Apr 9, 2010·Pneumologie·W WindischUNKNOWN Projektgruppe Nichtinvasive und invasive Beatmung als Therapie der chronischen respiratorischen Insuffizienz
Nov 7, 2012·Respiration; International Review of Thoracic Diseases·Jens BräunlichHubert Wirtz
Jul 9, 2014·American Journal of Respiratory and Critical Care Medicine·Salvatore Maurizio MaggioreMassimo Antonelli
May 20, 2015·JAMA : the Journal of the American Medical Association·François StéphanUNKNOWN BiPOP Study Group
May 20, 2015·The New England Journal of Medicine·Jean-Pierre FratUNKNOWN REVA Network

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Citations

Mar 8, 2016·The American Journal of Emergency Medicine·Victoria LepereJean-Damien Ricard
May 2, 2017·COPD·Lara Pisani, Maria Laura Vega
Jun 8, 2017·Respirology : Official Journal of the Asian Pacific Society of Respirology·Jens Bräunlich, Hubert Wirtz
Dec 21, 2017·Journal of Aerosol Medicine and Pulmonary Drug Delivery·Jens Bräunlich, Hubert Wirtz
Nov 9, 2018·Respirology : Official Journal of the Asian Pacific Society of Respirology·Jean-Pierre FratArnaud W Thille
Aug 11, 2017·European Respiratory Review : an Official Journal of the European Respiratory Society·Eleni IschakiSpyros Zakynthinos
May 15, 2019·Respirology : Official Journal of the Asian Pacific Society of Respirology·Steven McKinstryJames Fingleton
Sep 6, 2019·Respirology : Official Journal of the Asian Pacific Society of Respirology·Darren R Mansfield
Nov 19, 2019·Emergency Medicine International·Cheng-Chieh HuangYuan-Jhen Syue
Mar 27, 2020·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·Wanru GengHangyong He
Jun 21, 2018·Annals of the American Thoracic Society·Ralph J Panos
Jul 12, 2019·Reviews on Recent Clinical Trials·Andrea BruniFederico Longhini
Oct 16, 2019·Therapeutic Advances in Respiratory Disease·Samuel DolidonMaxime Patout
Sep 29, 2020·ERJ Open Research·Marlies van DijkMarieke L Duiverman
Dec 2, 2020·Journal of Clinical Medicine·Massa ZantahGerard J Criner
Dec 3, 2020·Sleep & Breathing = Schlaf & Atmung·Anna Christina MeyerMatthias Boentert
Dec 9, 2020·Pneumologie·P HaidlUNKNOWN Deutsche Sauerstoff- und BeatmungsLiga LOT e. V.
Dec 4, 2020·The Clinical Respiratory Journal·Abbas RezaeiHamidreza Jamaati
Jan 27, 2021·International Journal of Clinical Practice·Ozge Oral TapanLeyla Iyilikci Karaoglan
Jan 29, 2020·Respiration; International Review of Thoracic Diseases·Judith Elshof, Marieke L Duiverman

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NCT02007772

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