PMID: 2508467Oct 1, 1989Paper

Nasal intermittent positive-pressure ventilation offers no advantages over nasal continuous positive airway pressure in apnea of prematurity

American Journal of Diseases of Children
C A RyanK L Peters

Abstract

A prospective, randomized, cross-over trial was performed to compare the efficacy of nasal intermittent positive-pressure ventilation with nasal continuous positive airway pressure in infants of less than 32 weeks of gestation. Continuous positive airway pressure was delivered at end-expiratory pressures of 4 cm H2O, while peak pressures of 20 cm H2O and end-expiratory pressures of 4 cm H2O were used during nasal intermittent positive-pressure ventilation at ventilatory rates of 20 breaths per minute. The frequency and extent of apnea and bradycardia during a 6-hour period in a patient receiving nasal continuous positive airway pressure were compared with a similar crossover period of nasal intermittent positive-pressure ventilation. Although the infants had slightly less frequent episodes of apnea per hour (0.6 +/- 0.7 vs 0.5 +/- 0.7) and bradycardia per hour (1.2 +/- 1.3 vs 0.9 +/- 1.0) during nasal intermittent positive-pressure ventilation, these differences were not significant. There were no significant differences in the severity of these events as assessed by the duration and fall in transcutaneous oxygen pressure during apnea and heart rate during bradycardia. There were no significant changes in blood gases throughout...Continue Reading

Citations

Sep 8, 2012·Clinics in Perinatology·Vineet Bhandari
Jul 5, 2011·Paediatric Respiratory Reviews·Ramadan A MahmoudGerd Schmalisch
Oct 1, 2008·Early Human Development·Eduardo Bancalari, Nelson Claure
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Nov 16, 2007·The Journal of Perinatal & Neonatal Nursing·Debbie Fraser Askin
Dec 14, 2018·Medicine·Li-Bin DongShuang Qiao
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Sep 2, 2014·Reproductive Health·Rehana A SalamZulfiqar A Bhutta

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