Nasal mucosa narrow band imaging in granulomatosis with polyangiitis (Wegener granulomatosis): A preliminary study

American Journal of Rhinology & Allergy
Matteo TrimarchiMario Bussi

Abstract

Narrow band imaging (NBI) endoscopy is a technique that allows for real-time visualization of mucosal and submucosal vascular patterns. Because granulomatosis with polyangiitis (GPA) (Wegener granulomatosis) is an autoimmune disease defined by vascular inflammation, we examined patients with GPA and with NBI to evaluate whether disease-specific mucosal vascular patterns were present. To the best of our knowledge, the use of NBI endoscopy for assessment of an immune system disease such as GPA has never been previously attempted. We conducted a prospective observational study by performing an endoscopic evaluation of upper airways with NBI on patients diagnosed with GPA; on patients with symptoms and signs suggestive for GPA, who were scheduled to undergo nasal biopsy to confirm diagnosis; on patients affected by chronic rhinosinusitis with nasal polyps; and on healthy controls. We enrolled 69 patients. NBI vascular patterns in patients with GPA were consistently and recognizably different from healthy mucosal patterns in 53% of our cases. In patients with GPA, biopsy and NBI results were for the most part comparable, except for three cases. Nasal mucosa NBI endoscopy can be considered a promising rapid and noninvasive live imagi...Continue Reading

References

Mar 15, 1992·Annals of Internal Medicine·G S HoffmanA S Fauci
Feb 1, 1991·Human Pathology·T V ColbyR A DeRemee
Feb 1, 1991·Human Pathology·E A Del Buono, A Flint
Jan 1, 1990·APMIS. Supplementum·H Lehmann, B Kiefer
Apr 25, 2001·Arthritis and Rheumatism·J H StoneUNKNOWN International Network for the Study of the Systemic Vasculitides (INSSYS)
Jul 3, 2007·The American Journal of Medicine·Javier D FinkielmanUNKNOWN WGET Research Group
Mar 25, 2008·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Akihito WatanabeShigeyuki Sasaki
Nov 5, 2008·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Akihito WatanabeShigeyuki Sasaki
Mar 31, 2010·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Cesare PiazzaGiorgio Peretti
Feb 1, 2012·Head & Neck·Yen-Chun LinHsu-Huei Weng
Jul 19, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Marcos Martinez Del PeroDavid Jayne
Sep 4, 2012·Autoimmunity Reviews·Matteo TrimarchiPier Luigi Meroni
Sep 25, 2012·Current Opinion in Otolaryngology & Head and Neck Surgery·Cesare PiazzaPiero Nicolai
May 1, 2013·Japanese Journal of Clinical Oncology·Osamu KikuchiManabu Muto
Nov 28, 2013·American Journal of Rhinology & Allergy·Ivan Dimitrijevic, Lars Edvinsson

❮ Previous
Next ❯

Citations

Nov 28, 2017·Current Opinion in Otolaryngology & Head and Neck Surgery·Aman Khanna, Anshul Sama
May 16, 2015·American Journal of Rhinology & Allergy·Matthew A Rank
Feb 25, 2017·American Journal of Rhinology & Allergy·Brian D'AnzaRaj Sindwani
Jun 11, 2019·European Journal of Ophthalmology·Matteo TrimarchiMario Bussi
Dec 15, 2020·Current Opinion in Otolaryngology & Head and Neck Surgery·Ashoke R Khanwalkar, Kevin C Welch
Dec 16, 2020·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Dachuan FanYijing Ye

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
biopsies

Software Mentioned

EMEA

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Terapevticheskiĭ arkhiv
V D KreĭmerE A Kogan
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
Bin ChenJie-Ren Peng
Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Kwong-Ming FockNgai-Moh Law
© 2021 Meta ULC. All rights reserved