PMID: 20128508Feb 5, 2010

Nasal vestibular huge keratoacanthoma: an unusual site

Pakistan Journal of Biological Sciences : PJBS
N YazdaniA Kouhi

Abstract

Keratoacanthoma (KA) is a rapidly growing, low-grade neoplasm of pilo-sebaceous and hair follicle units which most often appears on the sun-exposed skin of the middle aged and older persons with multiple or localized occurrence. This tumor is dome-shaped nodule with a central keratinous plug. The etiology of this tumor is not obvious. Exposure to excessive sunlight is the most frequently noted responsible factor in the etiology of KA. About 80% of the tumors occur on the face. The histological features of the KA are often very similar to those of a cutaneous squamous cell carcinoma; however, the tumor structure usually provides a basis for their difference. There are many unusual cases of keratoacanthoma reported regarding site, size or other specifications. In this study, we excised a mass of nasal vestibule, a site far away sun-exposure. To our knowledge, this is the first case of nasal vestibular keratoacanthoma. For a clinician and a pathologist it is important to consider a benign lesion like Keratoacanthoma (KA) in the differential diagnosis of ulcerated nasal lesions and pay attention to differ it from Squamous Cell Carcinoma (SCC) which has a different and aggressive management.

References

Jan 29, 2008·Current Diabetes Reviews·Gang HuJaakko Tuomilehto

Citations

Dec 25, 2013·The American Journal of Dermatopathology·Jacqueline A Savage, John C Maize
Jun 7, 2017·Case Reports in Pathology·Jason E CohnKenneth Briskin

Related Concepts

Biopsy
Keratoacanthoma
Nasal Cavity
Nose Diseases
Dermatologic Disorders
Attention
Squamous Cell Carcinoma
Differential Diagnosis
Face
Neoplasms

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