PMID: 18182351Jan 10, 2008Paper

Nasopharyngeal carcinoma during pregnancy

Taiwanese Journal of Obstetrics & Gynecology
Tsung-I LinMin-Min Chou

Abstract

Nasopharyngeal carcinoma, particularly during pregnancy, rarely comes to medical attention before it spreads to the regional lymph nodes. We report a 26-year-old Taiwanese woman who suffered from persistent headache and purulent nasal discharge during mid-pregnancy. Magnetic resonance imaging examination showed a large soft tissue mass measuring 3 x 2 x 2 cm in the left nasopharynx at 31 weeks of gestation. Punch biopsy of the tumor was done, and the histopathologic report revealed poorly differentiated, non-keratinizing type of squamous cell carcinoma (T4N2M0). A female infant weighing 1,790 g was delivered by cesarean section at 33 weeks of gestation with Apgar scores of 5 and 8 at 1 and 5 minutes, respectively. The patient received chemotherapy and radiation therapy after delivery. She was disease-free for 3 years. Subsequently, the patient delivered a second healthy infant weighing 3,084 g in a consecutive pregnancy, with a 3-year birth interval. Her first and second child showed normal psychomotor development at 3 years and 6 months of age, respectively. The possibility of rare nasopharyngeal carcinoma should be considered in any pregnant woman with presenting symptoms of persistent headache and abnormal nasal discharge, a...Continue Reading

References

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Feb 1, 2000·International Journal of Cancer. Journal International Du Cancer·J M YuanM C Yu
Feb 15, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jin-Ching LinWen-Yi Wang
Sep 1, 2004·International Journal of Radiation Oncology, Biology, Physics·Jin-Ching LinAndy C Lin

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Citations

Nov 15, 2011·Otolaryngologia polska. The Polish otolaryngology·Krzysztof KicińskiCzesław Stankiewicz
Jun 25, 2015·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Yi-Kan ChengJun Ma
Jul 23, 2019·Head & Neck·Jennifer Le GuevelouJuliette Thariat

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