Abstract
Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have been associated with worse patient outcomes and higher costs of care than methicillin-susceptible (MSSA) infections. However, since prior studies found these differences, the healthcare landscape has changed, including widespread dissemination of community-associated strains of MRSA. We sought to provide updated estimates of the excess costs of MRSA infections. We conducted a retrospective analysis using data from the National Inpatient Sample from the Agency for Healthcare Research and Quality for the years 2010-2014. We calculated costs for hospitalizations, including MRSA- and MSSA-related septicemia and pneumonia infections, as well as MRSA- and MSSA-related infections from conditions classified elsewhere and of an unspecified site ("other infections"). Differences in the costs of hospitalization were estimated using propensity score-adjusted mortality outcomes for 2010-2014. In 2014, estimated costs were highest for pneumonia and sepsis-related hospitalizations. Propensity score-adjusted costs were significantly higher for MSSA-related pneumonia ($40725 vs $38561; P = .045) and other hospitalizations ($15578 vs $14792; P < .001) than for MRSA-rela...Continue Reading
References
Mar 19, 1999·Emerging Infectious Diseases·R J RubinA Moiduddin
Dec 20, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sara E CosgroveYehuda Carmeli
Feb 21, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John J EngemannKeith S Kaye
Jul 1, 1961·Journal of Clinical Pathology·M BARBER
Jun 11, 2004·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Carolyn Guertin McHugh, Lee W Riley
Mar 11, 2005·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Sara E CosgroveYehuda Carmeli
Mar 11, 2005·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Shelby D ReedVance G Fowler
Jun 21, 2005·Diagnostic Microbiology and Infectious Disease·Thomas P Lodise, Peggy S McKinnon
Oct 15, 2005·Medical Care·Hude QuanWilliam A Ghali
Sep 7, 2007·PharmacoEconomics·Andrew F Shorr
Apr 7, 2009·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Debby Ben-DavidLeonard A Mermel
Feb 27, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Gregory A FiliceRuth Lynfield
Apr 1, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Melissa K SchaeferArjun Srinivasan
May 3, 2011·PloS One·Michael Z DavidRobert S Daum
Mar 2, 2013·American Journal of Epidemiology·Eili Y KleinRamanan Laxminarayan
Jul 17, 2013·Health Services Research·Eva H DugoffElizabeth A Stuart
Nov 13, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michihiko GotoEli N Perencevich
Apr 23, 2015·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jennifer S McDanelMarin L Schweizer
Dec 6, 2016·Epidemiology and Infection·L MayL G Miller
Oct 12, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Eili Y KleinRamanan Laxminarayan
Citations
Aug 29, 2019·Journal of Breath Research·Carrie L Jenkins, Heather D Bean
Jul 31, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nicole M WhiteNicholas Graves
Jul 21, 2020·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·Alessandra B Garcia ReevesMorris Weinberger
May 30, 2019·Frontiers in Chemistry·Yi WangA-Dong Shen
Dec 17, 2020·International Journal of Environmental Research and Public Health·Xuemei ZhenHengjin Dong
Dec 30, 2020·Chemical Reviews·Jed F Fisher, Shahriar Mobashery
May 15, 2021·American Journal of Infection Control·Kengo InagakiCharlotte V Hobbs
Nov 2, 2019·ACS Chemical Biology·Navid J Ayon, William G Gutheil
Dec 4, 2020·ACS Infectious Diseases·Emma R GuibersonJeffrey M Spraggins