National surveillance of methicillin-resistant Staphylococcus aureus among hospitalized pediatric patients in Canadian acute care facilities, 1995-2007

The Pediatric Infectious Disease Journal
Anne MatlowCanadian Nosocomial Infection Surveillance Program

Abstract

Information relating to the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) among hospitalized pediatric patients is limited. This report describes results of national MRSA surveillance among Canadian hospitalized pediatric patients from 1995 to 2007. Surveillance was laboratory-based. Clinical and epidemiologic data were obtained by reviewing the medical records. Standardized definitions were used to determine MRSA infection. Isolates were characterized by pulsed-field gel electrophoresis, staphylococcal cassette chromosome mec typing and antimicrobial susceptibility testing. A total of 1262 pediatric patients were newly identified as MRSA positive from 1995 to 2007. Ages ranged from newborn to 17.9 years, 49% were infected with MRSA (51% colonized), skin and soft tissue infections accounted for the majority (59%) of MRSA infections and 57% were epidemiologically classified as community acquired (CA). The most common epidemic strain types isolated were CMRSA2/USA100/800, CMRSA10/USA300 and CMRSA7/USA400. Overall, MRSA rates per 10,000 patient days increased from 0.08 to 3.88. Since 2005, overall rates of CA-MRSA per 10,000 patient days have dramatically increased while healthcare-associated MRSA rates remain...Continue Reading

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Citations

Apr 23, 2013·The Journal of Antimicrobial Chemotherapy·Kimberly A NicholUNKNOWN Canadian Antimicrobial Resistance Alliance
Sep 26, 2012·Antimicrobial Agents and Chemotherapy·Fawziah MarraWilliam R Bowie
Sep 17, 2013·Current Pediatrics Reports·Michael Z David, Robert S Daum
Oct 8, 2013·Pediatric Clinics of North America·Rakesh D Mistry
Aug 15, 2014·Indian Journal of Pathology & Microbiology·Shipeng LiXuzhuang Shen

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