National Trends in Location of Death in Patients With End-Stage Liver Disease.

Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
Alyson KaplanRussell Rosenblatt

Abstract

Despite improvement in the care of patients with end-stage liver disease (ESLD), mortality is rising. In the United States, patients are increasingly choosing to die at hospice and home, but data in patients with ESLD are lacking. Therefore, this study aimed to describe the trends in location of death in patients with ESLD. We conducted a retrospective cross-sectional analysis using the Centers for Disease Control and Prevention Wide-Ranging OnLine Data for Epidemiologic Research from 2003 to 2018. Death location was categorized as hospice, home, inpatient facility, nursing home, or other. Comparisons were made between sex, age, ethnicity, race, region, and other causes of death. Comparisons were also made between rates of change (calculated as annual percent change), proportion of deaths in 2018, and multivariable logistic regression. A total of 535,261 deaths were attributed to ESLD-most were male, non-Hispanic, and White. The proportion of deaths at hospice and home increased during the study period from 0.2% to 10.6% and 20.3% to 25.7%, respectively. Whites had the highest proportion of deaths in hospice and home. In multivariable analysis, elderly patients were more likely to die in hospice or home (odds ratio [OR], 1.20; ...Continue Reading

References

Sep 1, 1990·BMJ : British Medical Journal·J TownsendM Piper
Nov 14, 2000·JAMA : the Journal of the American Medical Association·K E SteinhauserJ A Tulsky
Feb 24, 2001·Gastroenterology·G MarchesiniUNKNOWN Italian Study Group for quality of life in cirrhosis
Apr 30, 2005·Journal of Palliative Medicine·I J Higginson, G J Sen-Gupta
Jul 1, 2008·Journal of Palliative Medicine·Lilian Liou Cohen
Oct 9, 2008·JAMA : the Journal of the American Medical Association·Alexi A WrightHolly G Prigerson
Mar 10, 2010·Archives of Internal Medicine·Jane L GivensArlene S Ash
Sep 15, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Alexi A WrightHolly G Prigerson
Aug 28, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Zafrina PoonjaConstantine J Karvellas
Oct 1, 2013·Journal of Palliative Medicine·Kimberly S Johnson
Mar 20, 2014·Annual Review of Public Health·Mark T Hughes, Thomas J Smith
Aug 20, 2015·The New England Journal of Medicine·Amy S Kelley, R Sean Morrison
Jan 31, 2016·Current Opinion in Organ Transplantation·Jennifer C Lai
Oct 27, 2016·JAMA : the Journal of the American Medical Association·David Blumenthal, Melinda K Abrams
Sep 30, 2016·World Journal of Transplantation·Priya KathpaliaJennifer C Lai
Jun 3, 2017·Journal of Palliative Medicine·Marianne H SkorstengaardAnders B Jensen
Jul 18, 2017·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Haider AltaiiCarlos Romero-Marrero
May 8, 2018·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Chiara MazzarelliMary D Cannon
Jun 28, 2018·JAMA : the Journal of the American Medical Association·Joan M TenoVincent Mor
Jul 20, 2018·BMJ : British Medical Journal·Elliot B Tapper, Neehar D Parikh
Feb 28, 2019·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·W R KimB L Kasiske
Mar 20, 2019·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Nneka N UfereAreej El-Jawahri
Apr 10, 2019·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Nneka N UfereAreej El-Jawahri
Jul 22, 2019·Journal of Pain and Symptom Management·Nneka N UfereAreej El-Jawahri
Oct 12, 2019·Journal of the American College of Cardiology·Sarah H CrossHaider J Warraich
Oct 15, 2019·Journal of the American Geriatrics Society·Sarah H CrossHaider J Warraich
Dec 12, 2019·The New England Journal of Medicine·Sarah H Cross, Haider J Warraich
Mar 9, 2020·Digestive Diseases and Sciences·Jacqueline G O'LearyJasmohan S Bajaj

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Citations

Jan 12, 2021·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Kshitij Thakur, Jessica McFarlin
Jan 28, 2021·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Alyson KaplanRussell Rosenblatt

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