National trends in the ambulatory treatment of hypertension in the United States, 1997-2012

PloS One
Meijia ZhouG C Alexander

Abstract

Hypertension is common and costly. Over the past decade, new antihypertensive therapies have been developed, several have lost patent protection and additional evidence regarding the safety and effectiveness of these agents has accrued. To examine trends in the use of antihypertensive therapies in the United States between 1997 and 2012. We used nationally representative audit data from the IMS Health National Disease and Therapeutic Index to examine the ambulatory pharmacologic treatment of hypertension. Our primary unit of analysis was a visit where hypertension was a reported diagnosis and treated with a pharmacotherapy (treatment visit). We restricted analyses to the use of six therapeutic classes of antihypertensive medications among individuals 18 years or older. Annual hypertension treatment visits increased from 56.9 million treatment visits (95% confidence intervals [CI], 53.9-59.8) in 1997 to 83.3 million visits (CI 79.2-87.3) in 2008, then declined steadily to 70.9 million visits (CI 66.7-75.0) by 2012. Angiotensin receptor blocker utilization increased substantially from 3% of treatment visits in 1997 to 18% by 2012, whereas calcium channel blocker use decreased from 27% to 18% of visits. Rates of diuretic and beta-...Continue Reading

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Citations

May 23, 2017·American Journal of Hypertension·Shreya J Shah, Randall S Stafford
Sep 21, 2020·The Journal of Clinical Hypertension·Chris LaValleeTyler H Gums
Oct 20, 2020·Frontiers in Nutrition·Xiaoyu ZouChunbao Li
Nov 28, 2020·American Journal of Hypertension·Kathryn E FotiElizabeth Selvin

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