Nationwide implementation of laparoscopic surgery for colon cancer: short-term outcomes and long-term survival in a population-based cohort

Surgical Endoscopy
Kjartan StormarkHartwig Kørner

Abstract

Randomized trials show similar outcomes after open surgery and laparoscopy for colon cancer, and confirmation of outcomes after implementation in routine practice is important. While some studies have reported long-term outcomes after laparoscopic surgery from single institutions, data from large patient cohorts are sparse. We investigated short- and long-term outcomes of laparoscopic and open surgery for treating colon cancer in a large national cohort. We retrieved data from the Norwegian Colorectal Cancer Registry for all colon cancer resections performed in 2007-2010. Five-year relative survival rates following laparoscopic and open surgeries were calculated, including excess mortality rates associated with potential predictors of death. Among 8707 patients with colon cancer that underwent major resections, 16 % and 36 % received laparoscopic procedures in 2007 and 2010, respectively. Laparoscopic procedures were most common in elective surgeries for treating stages I-III, right colon, or sigmoid tumours. The conversion rate of laparoscopic procedures was 14.5 %. Among all patients, laparoscopy provided higher 5-year relative survival rates (70 %) than open surgery (62 %) (P = 0.040), but among the largest group of patients...Continue Reading

References

Jan 1, 1982·American Journal of Epidemiology·S Lemeshow, D W Hosmer
Jun 18, 2002·BMJ : British Medical Journal·Peter McCullochDamian Griffin
Dec 26, 2003·Statistics in Medicine·Paul W DickmanTimo Hakulinen
Jul 5, 2005·The Lancet Oncology·Ruben VeldkampUNKNOWN COlon cancer Laparoscopic or Open Resection Study Group (COLOR)
Mar 3, 2006·Computer Methods and Programs in Biomedicine·Maja Pohar, Janez Stare
Mar 22, 2007·Langenbeck's Archives of Surgery·Jens NeudeckerWolfgang Schwenk
Sep 26, 2007·Annals of Surgery·James FleshmanUNKNOWN Clinical Outcomes of Surgical Therapy Study Group
Dec 1, 2007·Epidemiology·Jan P VandenbrouckeUNKNOWN STROBE Initiative
Jul 6, 2010·The British Journal of Surgery·M BragaV Di Carlo
Jul 16, 2010·The British Journal of Surgery·D W BorowskiUNKNOWN Northern Region Colorectal Cancer Audit Group (NORCCAG)
Jun 22, 2011·Biometrics·Maja Pohar PermeJacques Estève
May 25, 2012·Reviews on Recent Clinical Trials·Kristoffer LassenTruls Myrmel
Apr 16, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·B S NedrebøUNKNOWN Norwegian Colorectal Cancer Group
Sep 5, 2013·Surgical Endoscopy·Monirah AlnasserJonathan E Efron
Nov 12, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M TheophilusK Spilsbury
Dec 21, 2014·Journal of the National Cancer Institute·Nicholas J Petrelli

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Citations

Oct 6, 2016·Surgical Endoscopy·Stefan BenzMonika Klinkhammer-Schalke
Oct 21, 2016·The British Journal of Surgery·A C CurrieR H Kennedy
Jan 19, 2018·Surgical Endoscopy·Michael P M de Neree Tot BabberichUNKNOWN Dutch Surgical Colorectal Audit
Mar 17, 2020·American Journal of Physiology. Gastrointestinal and Liver Physiology·Xiang LiCaijuan Li
Dec 6, 2017·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Roberto VerzaroStefano Necozione
Jun 30, 2018·World Journal of Surgical Oncology·Jörg O W PelzArmin Wiegering
Mar 14, 2018·International Journal of Colorectal Disease·Eligijus PoskusKestutis Strupas
Nov 16, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Corrado PedrazzaniAlfredo Guglielmi
Jul 3, 2017·Journal of the Egyptian National Cancer Institute·Ahmed Mostafa Ahmed Mahmoud, Manar Mohamed Moneer
Nov 28, 2020·Langenbeck's Archives of Surgery·Pere PlanellasAntoni Codina-Cazador
Dec 3, 2020·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·Carolin KastnerArmin Wiegering
Feb 2, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Renu R BahadoerJan Willem T Dekker
Nov 16, 2016·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Mario SaiaVincenzo Baldo
Apr 13, 2021·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Lucia GraneroJosé Luis Hernández Lizoáin
Aug 10, 2021·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Jorge BaixauliJosé L Hernández Lizoáin

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