Nationwide trends in the current management of desmoid (aggressive) fibromatosis

Clinical Oncology : a Journal of the Royal College of Radiologists
N C EastleyR U Ashford

Abstract

The optimal management of desmoid fibromatosis remains unclear, leading to significant variability in patient management. To assess this problem, the current approach of clinicians managing this complex condition in the UK was investigated. A hypothetical case of intramuscular limb girdle desmoid fibromatosis in a fit 65-year-old patient was devised. Surgical and non-surgical oncology members of the British Sarcoma Group were questioned on how they would manage this case in three scenarios: primary disease with function-sparing surgery possible, primary disease with neurovascular involvement and disease recurrence after a previous R0 resection. Initial management, management of symptomatic disease progression, follow-up preferences and any differences in respondents' management choices in a younger case were investigated. The responses from 14 sarcoma surgeons and 23 oncologists (14 clinical, nine medical) were analysed. Desmoid fibromatosis management is generally shared by surgeons and oncologists within sarcoma multidisciplinary teams in the UK. Variation exists in the chosen initial management of primary desmoid fibromatosis in the UK, with function-sparing surgery possible (observation 51%, resection 51%), primary desmoid ...Continue Reading

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Citations

Oct 17, 2015·Expert Review of Anticancer Therapy·Mushriq Al-JazraweBenjamin Alman
Mar 12, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·N EastleyR Ashford
Oct 22, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·D MaY Xiao
Aug 10, 2016·Skeletal Radiology·Pooja J ShethTy K Subhawong
Aug 21, 2016·The Surgical Clinics of North America·Valerie P GrignolJohn Harrison Howard
May 15, 2018·Nursing·Janette OʼSullivan, Margaret Vanderbeek-Warren
Apr 23, 2019·Annals of Plastic Surgery·Hiroaki KuwaharaErkki Tukiainen
Jan 1, 2016·Oncology and Therapy·J Harrison Howard, Raphael E Pollock
Mar 27, 2020·Journal of Surgical Oncology·Samir SabharwalCarol D Morris
Jun 6, 2021·BMJ Case Reports·Kishore AbujiDivya Dahiya

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