PMID: 6990230Apr 1, 1980Paper

Natulan, a bacterial mutagen requiring complex mammalian metabolic activation

Mutation Research
A K Solt, S Neale

Abstract

Following administration of Natulan and Escherichia coli to mice a dose-dependent increase in the frequency of induced bacterial mutations was observed. This mutation response was dependent on the route of Natulan administration and, following short exposures, was limited by the rate of metabolic activation of the compound.

References

Jan 1, 1978·Mutation Research·I P Lee, R L Dixon
Feb 1, 1979·Mutation Research·U H Ehling, A Neuhäuser
Mar 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·J McCann, B N Ames
Dec 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J McCannB N Ames
Dec 1, 1973·Environmental Health Perspectives·H V Malling, C N Frantz
Aug 24, 1974·British Medical Journal·H M PinedoJ Van der Sluys Veer
Dec 1, 1974·Annals of Internal Medicine·S D Spivack

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